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GCKR Products

(Glucokinase (Hexokinase 4) Regulator (GCKR))
This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY). [provided by RefSeq, Jul 2008].

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Featured GCKR Categories

GCKR Antibodies

High quality antibodies with extensive validation data.

GCKR ELISA Kits

Reliable ELISA kits for a wide range of species.

GCKR Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GCKR Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7442828
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7442180
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7153892
Quantity 100 μg
Datasheet Datasheet

Recommended GCKR ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN5648260
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5594592
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN509974
Quantity 96 tests
Datasheet Datasheet

Recommended GCKR Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3080621
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3127421
Quantity 1 mg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7405930
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our GCKR products

Jin, Guo, Li, Lei, Li, Mao, Wang, Zhou, Zhang, Hu, Zhang, Niu, Irwin, Tan: "Role of glucokinase in the subcellular localization of glucokinase regulatory protein." in: International journal of molecular sciences, Vol. 16, Issue 4, pp. 7377-93, (2015) (PubMed).

Tomilov, Bettaieb, Kim, Sahdeo, Tomilova, Lam, Hagopian, Connell, Fong, Rowland, Griffey, Ramsey, Haj, Cortopassi: "Shc depletion stimulates brown fat activity in vivo and in vitro." in: Aging cell, Vol. 13, Issue 6, pp. 1049-58, (2014) (PubMed).

Kathiresan, Melander, Guiducci, Surti, Burtt, Rieder, Cooper, Roos, Voight, Havulinna, Wahlstrand, Hedner, Corella, Tai, Ordovas, Berglund, Vartiainen, Jousilahti, Hedblad, Taskinen, Newton-Cheh et al.: "Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans. ..." in: Nature genetics, Vol. 40, Issue 2, pp. 189-97, (2008) (PubMed).

Veiga-da-Cunha, Delplanque, Gillain, Bonthron, Boutin, Van Schaftingen, Froguel: "Mutations in the glucokinase regulatory protein gene in 2p23 in obese French caucasians." in: Diabetologia, Vol. 46, Issue 5, pp. 704-11, (2003) (PubMed).

Synonyms and alternative names related to GCKR

glucokinase regulator (GCKR), glucokinase regulator (Gckr), glucokinase regulatory protein (Gckr), glucokinase regulator L homeolog (gckr.L), FGQTL5, gckr, GKRP, GLRE

Protein level used designations for GCKR

  • glucokinase regulatory protein
  • glucokinase regulator
  • LOW QUALITY PROTEIN: glucokinase regulatory protein
  • glucokinase (hexokinase 4) regulator
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