HAX1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
-
- Target See all HAX1 Proteins
- HAX1 (HCLS1 Associated Protein X-1 (HAX1))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This HAX1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
-
- Recombinant human HAX1 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product HAX1 Protein
-
-
- Application Notes
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
-
The tag is located at the C-terminal.
- Restrictions
- For Research Use only
-
- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
- Target
- HAX1 (HCLS1 Associated Protein X-1 (HAX1))
- Alternative Name
- Hax1 (HAX1 Products)
- Synonyms
- HAX1 Protein, hax1 Protein, HCLSBP1 Protein, HS1BP1 Protein, SCN3 Protein, HAX-1 Protein, Hs1bp1 Protein, HSP1BP-1 Protein, SIG-111 Protein, Silg111 Protein, mHAX-1s Protein, HCLS1 associated protein X-1 Protein, HCLS1 associated X-1 Protein, HAX1 Protein, hax1 Protein, Hax1 Protein
- Background
- The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
- 31.4 kDa
- NCBI Accession
- NP_006109
- Pathways
- Regulation of Actin Filament Polymerization
-