IFI16 Protein (Myc-DYKDDDDK Tag)
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- Target See all IFI16 Proteins
- IFI16 (Interferon, gamma-Inducible Protein 16 (IFI16))
- Protein Type
- Recombinant
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IFI16 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human IFI16 / IFNGIP1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product IFI16 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- IFI16 (Interferon, gamma-Inducible Protein 16 (IFI16))
- Alternative Name
- Ifi16,ifngip1 (IFI16 Products)
- Synonyms
- IFNGIP1 Protein, PYHIN2 Protein, IFI16 Protein, Ifitm3l Protein, Ifitml Protein, interferon gamma inducible protein 16 Protein, interferon induced transmembrane protein 2 Protein, myeloid cell nuclear differentiation antigen-like protein Protein, interferon-activable protein 203 Protein, IFI16 Protein, Ifitm2 Protein, LOC100156073 Protein, LOC488622 Protein, Ifi16 Protein
- Background
- This gene encodes a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
- 81.9 kDa
- NCBI Accession
- NP_005522
- Pathways
- Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Autophagy, Inflammasome
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