LGR5 Protein (Fc Tag)

Catalog No. ABIN2724698

Product Details

Target: LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This LGR5 protein is labelled with Fc Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human LGR5 / GPR49 (C-term Fc tag) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: DPBS, 10 % glycerol

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))

Alternative Name: Lgr5,gpr49 (LGR5 Products)

Synonyms: lgr5-a Protein, lgr5a Protein, FEX Protein, Gpr49 Protein, GPR49 Protein, GPR67 Protein, GRP49 Protein, HG38 Protein, leucine-rich repeat containing G protein-coupled receptor 5 L homeolog Protein, leucine rich repeat containing G protein coupled receptor 5 Protein, leucine rich repeat containing G protein-coupled receptor 5 Protein, lgr5.L Protein, Lgr5 Protein, LGR5 Protein

Background: The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 38 kDa

NCBI Accession: NP_003658

Pathways: WNT Signaling