PPM1B Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all PPM1B Proteins
- PPM1B (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B (PPM1B))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PPM1B protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Protein phosphatase 1B / PPM1B (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PPM1B Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- PPM1B (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B (PPM1B))
- Alternative Name
- Protein Phosphatase 1b,ppm1b (PPM1B Products)
- Synonyms
- PP2C-beta-X Protein, PP2CB Protein, PP2CBETA Protein, PPC2BETAX Protein, Pp2c2 Protein, fc18g04 Protein, ppm1a Protein, wu:fc18g04 Protein, zgc:92329 Protein, pp2c-beta-x Protein, pp2cb Protein, pp2cbeta Protein, ppc2betax Protein, zgc:92031 Protein, protein phosphatase, Mg2+/Mn2+ dependent 1B Protein, protein phosphatase 1B, magnesium dependent, beta isoform Protein, protein phosphatase, Mg2+/Mn2+ dependent, 1B Protein, protein phosphatase, Mg2+/Mn2+ dependent, 1Bb Protein, protein phosphatase, Mg2+/Mn2+ dependent 1B L homeolog Protein, protein phosphatase, Mg2+/Mn2+ dependent, 1Ba Protein, PPM1B Protein, Ppm1b Protein, ppm1bb Protein, ppm1b.L Protein, ppm1ba Protein
- Background
- The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences.
- Molecular Weight
- 52.5 kDa
- NCBI Accession
- NP_002697
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