RABGEF1 Protein (Myc-DYKDDDDK Tag)
-
- Target See all RABGEF1 Proteins
- RABGEF1 (RAB Guanine Nucleotide Exchange Factor (GEF) 1 (RABGEF1))
- Protein Type
- Recombinant
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This RABGEF1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
-
- Recombinant human RABGEF1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product RABGEF1 Protein
-
-
- Application Notes
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
-
The tag is located at the C-terminal.
- Restrictions
- For Research Use only
-
- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
- Target
- RABGEF1 (RAB Guanine Nucleotide Exchange Factor (GEF) 1 (RABGEF1))
- Alternative Name
- Rabgef1 (RABGEF1 Products)
- Synonyms
- Rab5ef Protein, Rabex5 Protein, Rin2 Protein, RABEX5 Protein, rabex-5 Protein, rabgef1 Protein, RAB guanine nucleotide exchange factor (GEF) 1 Protein, RAB guanine nucleotide exchange factor 1 Protein, RAB guanine nucleotide exchange factor (GEF) 1 L homeolog Protein, Rabgef1 Protein, RABGEF1 Protein, rabgef1.L Protein
- Background
- RABGEF1 forms a complex with rabaptin-5 (RABPT5 MIM 603616) that is required for endocytic membrane fusion, and it serves as a specific guanine nucleotide exchange factor (GEF) for RAB5 (RAB5A MIM 179512) (Horiuchi et al., 1997 [PubMed 9323142]).[supplied by OMIM, Mar 2010].
- Molecular Weight
- 56.7 kDa
- NCBI Accession
- NP_055319
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
-