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RUNX3 Protein (His tag)

RUNX3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2731258
  • Target See all RUNX3 Proteins
    RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))
    Protein Type
    Recombinant
    Origin
    • 5
    • 3
    • 1
    Human
    Source
    • 4
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This RUNX3 protein is labelled with His tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human RUNX3 (full length, N-term HIS tag, transcript variant 1) protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product RUNX3 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the N-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    50 mM Tris,8M Urea, pH 8.0.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))
    Alternative Name
    Runx3 (RUNX3 Products)
    Synonyms
    runxb Protein, RUNX3 Protein, CBFA3 Protein, frrunx3 Protein, runx3 Protein, aml2 Protein, cbfa3 Protein, pebp2ac Protein, AML2 Protein, Cbfa3 Protein, Pebp2a3 Protein, PEBP2aC Protein, runt-related transcription factor 3 Protein, runt related transcription factor 3 Protein, runt related transcription factor 3 L homeolog Protein, runx3 Protein, RUNX3 Protein, runx3.L Protein, Runx3 Protein
    Background
    This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants.
    Molecular Weight
    45.7 kDa
    NCBI Accession
    NP_001026850
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