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SUN2 Protein (Myc-DYKDDDDK Tag)

SUN2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2732986
  • Target See all SUN2 Proteins
    SUN2 (Sad1 and UNC84 Domain Containing 2 (SUN2))
    Protein Type
    Recombinant
    Origin
    • 4
    • 3
    Human
    Source
    • 4
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This SUN2 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human SUN2 / UNC84B protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product SUN2 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    SUN2 (Sad1 and UNC84 Domain Containing 2 (SUN2))
    Alternative Name
    Sun2,unc84b (SUN2 Products)
    Synonyms
    UNC84B Protein, B230369L08Rik Protein, C030011B15 Protein, Unc84b Protein, RGD1563141 Protein, Sad1 and UNC84 domain containing 2 Protein, SUN2 Protein, Sun2 Protein
    Background
    SUN1 (MIM 607723) and SUN2 are inner nuclear membrane (INM) proteins that play a major role in nuclear-cytoplasmic connection by formation of a 'bridge' across the nuclear envelope, known as the LINC complex, via interaction with the conserved luminal KASH domain of nesprins (e.g., SYNE1 MIM 608441) located in the outer nuclear membrane (ONM). The LINC complex provides a direct connection between the nuclear lamina and the cytoskeleton, which contributes to nuclear positioning and cellular rigidity (summary by Haque et al., 2010 [PubMed 19933576]).[supplied by OMIM, Nov 2010].
    Molecular Weight
    80.1 kDa
    NCBI Accession
    NP_056189
    Pathways
    Maintenance of Protein Location, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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