TAPBP Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all TAPBP Proteins
- TAPBP (TAP Binding Protein (Tapasin) (TAPBP))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TAPBP protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Tapasin (TAPBP) (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product TAPBP Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- TAPBP (TAP Binding Protein (Tapasin) (TAPBP))
- Alternative Name
- Tapasin (Tapbp) (TAPBP Products)
- Synonyms
- SI:dZ179B20.1 Protein, SI:dZ179B20.3 Protein, SI:dZ179B20.7 Protein, mhc1uda Protein, mhc1ufa Protein, tpsn Protein, zgc:109814 Protein, tapbp Protein, TAPBP Protein, D17Wsu91e Protein, TPN Protein, NGS17 Protein, TAPA Protein, TPSN Protein, TAP binding protein (tapasin), tandem duplicate 1 Protein, TAP binding protein Protein, tapbp.1 Protein, tapbp Protein, TAPBP Protein, Tapbp Protein
- Background
- This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.
- Molecular Weight
- 45.6 kDa
- NCBI Accession
- NP_003181
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