TRIB2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all TRIB2 Proteins
- TRIB2 (Tribbles Pseudokinase 2 (TRIB2))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TRIB2 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human TRIB2 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product TRIB2 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- TRIB2 (Tribbles Pseudokinase 2 (TRIB2))
- Alternative Name
- Trib2 (TRIB2 Products)
- Synonyms
- TRIB2 Protein, Trb2 Protein, Xtrbl Protein, gs3955 Protein, c5fw Protein, trb2 Protein, xtrb2 Protein, TRB2 Protein, C5FW Protein, GS3955 Protein, TRB-2 Protein, AW319517 Protein, RGD1564451 Protein, tribbles pseudokinase 2 Protein, tribbles pseudokinase 2 S homeolog Protein, TRIB2 Protein, trib2 Protein, trib2.S Protein, Trib2 Protein
- Background
- This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene.
- Molecular Weight
- 38.6 kDa
- NCBI Accession
- NP_067675
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