TRIB2 Protein (GST tag,His tag)
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- Target See all TRIB2 Proteins
- TRIB2 (Tribbles Pseudokinase 2 (TRIB2))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This TRIB2 protein is labelled with GST tag,His tag.
- Purpose
- Recombinant Human TRIB2/TRB2 Protein (His & GST Tag)
- Sequence
- Met 1-Asn 343
- Characteristics
- A DNA sequence encoding the human TRIB2 (NP_067675.1) (Met 1-Asn 343) was fused with the GST tag at the N-terminus and a polyhistidine tag at the C-terminus.
- Purity
- > 90 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product TRIB2 Protein
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Tribbles Pseudokinase 2 (TRIB2) (AA 1-343) protein (GST tag)
TRIB2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Tribbles Pseudokinase 2 (TRIB2) (AA 254-343) protein (GST tag)TRIB2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Tribbles Pseudokinase 2 (TRIB2) (AA 1-343) protein (Strep Tag)Crystallography grade TRIB2 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Tribbles Pseudokinase 2 (TRIB2) (AA 1-343) protein (Strep Tag)Crystallography grade TRIB2 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Tribbles Pseudokinase 2 (TRIB2) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)TRIB2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as sterile 50 mM Tris, 100 mM NaCl, 0.5 mM PMSF, 0.5 mM GSH, pH 8.0
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- TRIB2 (Tribbles Pseudokinase 2 (TRIB2))
- Alternative Name
- TRIB2/TRB2 (TRIB2 Products)
- Synonyms
- TRIB2 Protein, Trb2 Protein, Xtrbl Protein, gs3955 Protein, c5fw Protein, trb2 Protein, xtrb2 Protein, TRB2 Protein, C5FW Protein, GS3955 Protein, TRB-2 Protein, AW319517 Protein, RGD1564451 Protein, tribbles pseudokinase 2 Protein, tribbles pseudokinase 2 S homeolog Protein, TRIB2 Protein, trib2 Protein, trib2.S Protein, Trib2 Protein
- Background
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Background: Tribbles homolog 2, also known as TRB-2, and Trib2, is a member of the protein kinase superfamily and Tribbles subfamily (Trib1, Trib2, Trib3). The identification of tribbles as regulators of signal processing systems and physiological processes, including development, together with their potential involvement in diabetes and cancer, has generated considerable interest in these proteins. Tribbles have been reported to regulate activation of a number of intracellular signalling pathways with roles extending from mitosis and cell activation to apoptosis and modulation of gene expression. Tribbles controls the timing of mitosis in the prospective mesoderm, allowing cell-shape changes to be completed. This mechanism for coordinating cell division and cell-shape changes may have helped Drosophila to evolve its mode of rapid early development. Trib2 was identified as a downregulated transcript in leukemic cells undergoing growth arrest. Trib2-transduced bone marrow cells exhibited a growth advantage and readily established factor-dependent cell lines. Trib2-reconstituted mice uniformly developed fatal transplantable acute myelogenous leukemia (AML).
Synonym: C5FW,FLJ57420,GS3955,TRB2,TRIB2
- Molecular Weight
- 66 kDa
- NCBI Accession
- NP_067675
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