Ccl12 Protein

Catalog No. ABIN2830167

Product Details

Target: Ccl12 (Chemokine (C-C Motif) Ligand 12 (Ccl12))

Protein Type: Recombinant

Biological Activity: Active

Origin: Mouse

Source: Escherichia coli (E. coli)

Application: Functional Studies (Func)

Sequence: GPDAVSTPVT CCYNVVKQKI HVRKLKSYRR ITSSQCPREA VIFRTILDKE ICADPKEKWV KNSINHLDKT SQTFILEPSC LG

Characteristics: Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral blood monocytes is in a concentration range of 10-50 ng/mL.

Purity: >95 % as determined by SDS-PAGE and HPLC.

Sterility: 0.2 μm filtered

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: PBS, pH 7.4

Storage: -20 °C

Target Details

Target: Ccl12 (Chemokine (C-C Motif) Ligand 12 (Ccl12))

Alternative Name: Ccl12 (Ccl12 Products)

Synonyms: MCP-5 Protein, Scya12 Protein, chemokine (C-C motif) ligand 12 Protein, Ccl12 Protein

Background: Relevance: Chemotactic factor that attracts eosinophils, monocytes, and lymphocytes but not neutrophils. Potent monocyte active chemokine that signals through CCR2. Involved in allergic inflammation and the host response to pathogens and may play a pivotal role during early stages of allergic lung inflammation.
Synonyms: MCP-1-related chemokine, Monocyte chemotactic protein 5, MCP-5, Small-inducible cytokine A12,

Molecular Weight: 9.3 kDa

UniProt: Q62401

Pathways: Cellular Response to Molecule of Bacterial Origin