LMAN2 Protein (AA 45-322) (His tag)
-
- Target See all LMAN2 Proteins
- LMAN2 (Lectin, Mannose-Binding 2 (LMAN2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 45-322
- Origin
- Human
-
Source
- Human Cells
- Purification tag / Conjugate
- This LMAN2 protein is labelled with His tag.
- Purpose
- Recombinant Human VIP36/LMAN2/GP36b (C-6His)
- Sequence
- DITDGNSEHL KREHSLIKPY QGVGSSSMPL WDFQGSTMLT SQYVRLTPDE RSKEGSIWNH QPCFLKDWEM HVHFKVHGTG KKNLHGDGIA LWYTRDRLVP GPVFGSKDNF HGLAIFLDTY PNDETTERVF PYISVMVNNG SLSYDHSKDG RWTELAGCTA DFRNRDHDTF LAVRYSRGRL TVMTDLEDKN EWKNCIDITG VRLPTGYYFG ASAGTGDLSD NHDIISMKLF QLMVEHTPDE ESIDWTKIEP SVNFLKSPKD NVDDPTGNFR SGPLTGWRVD HHHHHH
- Characteristics
- Recombinant Human Vesicular Integral-Membrane Protein VIP36/LMAN2 is produced by our mammalian expression system. The target protein is expressed with sequence (Asp45-Arg322) of Human LMAN2 fused with a polyhistidine tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product LMAN2 Protein
-
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
-
It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Lyophilized from a 0.2 μm filtered solution of 50 mM TrisHCl,10 mM GSH, pH 8.0.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- 4 °C/-20 °C/-80 °C
- Storage Comment
-
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - Expiry Date
- 3 months
-
- Target
- LMAN2 (Lectin, Mannose-Binding 2 (LMAN2))
- Alternative Name
- LMAN2 (LMAN2 Products)
- Synonyms
- Lman2 Protein, wu:fb16f04 Protein, zgc:158761 Protein, C5orf8 Protein, GP36B Protein, VIP36 Protein, 1110003H06Rik Protein, 1300009F09Rik Protein, AA408240 Protein, AL023023 Protein, AU040819 Protein, Vip36 Protein, lectin, mannose binding 2 Protein, lectin, mannose-binding 2 Protein, LMAN2 Protein, lman2 Protein, Lman2 Protein
- Sub Type
- Fusionprotein
- Background
-
Vesicular integral-membrane protein VIP36 is also known as Glycoprotein GP36b, Lectin mannose-binding 2, Vesicular integral-membrane protein 36, LMAN2 and C5orf8. LMAN2 is widely expressed and contains one L-type lectin-like domain. LMAN2 binds high mannose type glycoproteins and may facilitate their sorting, trafficking and quality control. LMAN2 plays a role as an intracellular lectin in the early secretory pathway. LMAN2 interacts with N-acetyl-D-galactosamine and high-mannose type glycans and may also bind to O-linked glycans. LMAN2 is also involved in the transport and sorting of glycoproteins carrying high mannose-type glycans.
Alternative Names: Vesicular Integral-Membrane Protein VIP36, Glycoprotein GP36b, Lectin Mannose-Binding 2, Vesicular Integral-Membrane Protein 36, VIP36, LMAN2, C5orf8 - Molecular Weight
- 32.7 kDa
- UniProt
- Q12907
- Pathways
- SARS-CoV-2 Protein Interactome
-