RNF7 Protein (AA 2-113) (His tag)
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- Target See all RNF7 Proteins
- RNF7 (Ring Finger Protein 7 (RNF7))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 2-113
- Origin
- Human
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Source
- Yeast
- Purification tag / Conjugate
- This RNF7 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- ADVEDGEETC ALASHSGSSG SKSGGDKMFS LKKWNAVAMW SWDVECDTCA ICRVQVMDAC LRCQAENKQE DCVVVWGECN HSFHNCCMSL WVKQNNRCPL CQQDWVVQRI GK
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product RNF7 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- RNF7 (Ring Finger Protein 7 (RNF7))
- Alternative Name
- RBX2 (RNF7 Products)
- Synonyms
- CKBBP1 Protein, ROC2 Protein, SAG Protein, Rbx2 Protein, ring finger protein 7 Protein, RNF7 Protein, Rnf7 Protein
- Background
- Probable component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Through the RING-type zinc finger, ses to recruit the E2 ubiquitination enzyme to the complex and brings it into close proximity to the substrate. Promotes the neddylation of CUL5 via its interaction with UBE2F. May play a role in protecting cells from apoptosis induced by redox agents.
- Molecular Weight
- 14.5 kDa
- UniProt
- Q9UBF6
- Pathways
- Positive Regulation of Endopeptidase Activity
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