RNF7 Protein (AA 1-113) (His tag)
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- Target See all RNF7 Proteins
- RNF7 (Ring Finger Protein 7 (RNF7))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-113
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This RNF7 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSMADVEDG EETCALASHS GSSGSKSGGD KMFSLKKWNA VAMWSWDVEC DTCAICRVQV MDACLRCQAE NKQEDCVVVW GECNHSFHNC CMSLWVKQNN RCPLCQQDWV VQRIGK
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product RNF7 Protein
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Ring Finger Protein 7 (RNF7) (AA 1-113) protein (GST tag)
RNF7 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Ring Finger Protein 7 (RNF7) (AA 2-113) protein (His tag)Crystallography grade RNF7 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
Ring Finger Protein 7 (RNF7) (AA 2-113) protein (His tag)Crystallography grade RNF7 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
Ring Finger Protein 7 (RNF7) (AA 2-113) protein (GST tag)RNF7 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Ring Finger Protein 7 (RNF7) (AA 2-113) protein (His tag)RNF7 Origin: Human Host: Yeast Recombinant > 90 % SDS
Ring Finger Protein 7 (RNF7) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)RNF7 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Denatured
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.0 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 10 % glycerol, 0.4M urea
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- RNF7 (Ring Finger Protein 7 (RNF7))
- Alternative Name
- RNF7 (RNF7 Products)
- Synonyms
- CKBBP1 Protein, ROC2 Protein, SAG Protein, Rbx2 Protein, ring finger protein 7 Protein, RNF7 Protein, Rnf7 Protein
- Background
- RNF7 is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHuK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported. Recombinant human RNF7 protein, fused to His-tag at N-terminus, was expressed in E.coli .
- Molecular Weight
- 15.1 kDa (136aa)
- NCBI Accession
- NP_055060
- UniProt
- Q9UBF6
- Pathways
- Positive Regulation of Endopeptidase Activity
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