P-Selectin Protein (partial) (His tag)
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- Target See all P-Selectin (SELP) Proteins
- P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))
- Protein Type
- Recombinant
- Protein Characteristics
- partial
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This P-Selectin protein is labelled with His tag.
- Application
- Western Blotting (WB)
- Sequence
- Trp 42 - Ala 771
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Endotoxin level is less than 1.0 EU per ug by the LAL method.
- Top Product
- Discover our top product SELP Protein
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Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) protein (His-Avi Tag,Biotin)
SELP Origin: Human Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) (AA 42-709) protein (His tag)SELP Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) protein (Fc Tag)SELP Origin: Mouse Host: Human Cells Recombinant > 90 % as determined by reducing SDS-PAGE.
Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) protein (Fc Tag)SELP Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) (AA 1-829) protein (GST tag)SELP Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) (Active) protein (His tag)SELP Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) protein (His tag,AVI tag)SELP Origin: Mouse Host: Human Cells Recombinant > 90 % as determined by reducing SDS-PAGE.
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- Application Notes
- This recombinant protein can be used for WB.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C.
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- Target
- P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))
- Alternative Name
- P-Selectin (SELP Products)
- Synonyms
- PSELECT Protein, CD62 Protein, CD62P Protein, GMP140 Protein, GRMP Protein, LECAM3 Protein, PADGEM Protein, PSEL Protein, GMP-140 Protein, Grmp Protein, selectin P Protein, selectin, platelet Protein, Selp Protein, SELP Protein
- Background
- P-selectin (SELP) is also known as CD62 antigen-like family member P, granule membrane protein 140 (GMP-140), leukocyte-endothelial cell adhesion molecule 3 (LECAM3) and platelet activation dependent granule-external membrane protein (PADGEM). SELP functions as a cell adhesion molecule (CAM) on the surfaces of activated endothelial cells, which line the inner surface of blood vessels, and activated platelets. In unactivated endothelial cells, it is stored in granules called Weibel-Palade bodies. In unactivated platelets SELP is stored in alpha-granules. The primary ligand for SELP is P-selectin glycoprotein ligand-1 (PSGL-1) which is expressed on almost all leukocytes, although P-selectin also binds to heparan sulfate and fucoidan. Furthermore, SELP has a functional role in metastasis of tumor similar to E-selectin, which can help cancer cells invade into bloodstream for metastasis and provided locally with multiple growth factors respectively.
- Molecular Weight
- 81.8 kDa
- Gene ID
- 6403
- UniProt
- P16109
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