CSTB Protein (AA 1-98, full length) (GST tag)
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- Target See all CSTB Proteins
- CSTB (Cystatin B (Stefin B) (CSTB))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-98, full length
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CSTB protein is labelled with GST tag.
- Application
- SDS-PAGE (SDS), Western Blotting (WB), ELISA
- Sequence
- MMCGAPSATQ PATAETQHIA DQVRSQLEEK ENKKFPVFKA VSFKSQVVAG TNYFIKVHVG DEDFVHLRVF QSLPHENKPL TLSNYQTNKA KHDELTYF
- Purity
- 95 %
- Top Product
- Discover our top product CSTB Protein
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Cystatin B (Stefin B) (CSTB) (AA 1-98) protein (GST tag)
CSTB Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Cystatin B (Stefin B) (CSTB) (AA 1-98) protein (Strep Tag)Crystallography grade CSTB Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Cystatin B (Stefin B) (CSTB) (AA 1-98) (Active) protein (His tag)CSTB Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS Active
Cystatin B (Stefin B) (CSTB) proteinCSTB Origin: Cow Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, ELISA, IP
Cystatin B (Stefin B) (CSTB) protein (Myc-DYKDDDDK Tag)CSTB Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS buffer, 20mM GSH.
- Storage
- 4 °C
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- Target
- CSTB (Cystatin B (Stefin B) (CSTB))
- Alternative Name
- Cystatin-B (CSTB Products)
- Synonyms
- CST6 Protein, EPM1 Protein, EPM1A Protein, PME Protein, STFB Protein, ULD Protein, CSTB Protein, Cyb Protein, Epm1 Protein, Stfb Protein, MGC189005 Protein, pme Protein, cst6 Protein, epm1 Protein, stfb Protein, AA960480 Protein, ARABIDOPSIS THALIANA PHYTOCYSTATIN 6 Protein, ATCYS6 Protein, ATCYSB Protein, cystatin B Protein, LOC100008600 Protein, LOC100136235 Protein, CPI1 Protein, cystatin B Protein, cystatin B (stefin B) Protein, cystatin 14a, tandem duplicate 2 Protein, cystatin-B Protein, CSTB Protein, Cstb Protein, cstb Protein, cst14a.2 Protein, CYSB Protein, cpi1 Protein, LOC101123265 Protein
- Background
- Background: This is an intracellular thiol proteinase inhibitor. Tightly binding reversible inhibitor of cathepsins L, H and B. Defects in CSTB are the cause of progressive myoclonic epilepsy type 1 (EPM1) [MIM:254800]. EPM1 is an autosomal recessive disorder characterized by severe, stimulus-sensitive myoclonus and tonic-clonic seizures. The onset, occurring between 6 and 13 years of age, is characterized by convulsions. Myoclonus begins 1 to 5 years later. The twitchings occur predominantly in the proximal muscles of the extremities and are bilaterally symmetrical, although asynchronous. At first small, they become late in the clinical course so violent that the victim is thrown to the floor. Mental deterioration and eventually dementia develop. Synonyms: CPI-B Liver thiol proteinase inhibitor Stefin-B.
- Molecular Weight
- 38.5 kD
- NCBI Accession
- NM_000100
- UniProt
- P04080
- Pathways
- Response to Water Deprivation
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