GDF5 Protein (AA 382-501) (His tag)
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- Target See all GDF5 Proteins
- GDF5 (Growth Differentiation Factor 5 (GDF5))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 382-501
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This GDF5 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- GDF-5, 382-501aa, Human, His-tagged, Recombinant, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product GDF5 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 10 mM Sodium citrate pH 3.5, 10% glycerol
- Storage
- 4 °C
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- Target
- GDF5 (Growth Differentiation Factor 5 (GDF5))
- Alternative Name
- GDF-5 (GDF5 Products)
- Synonyms
- CDMP1 Protein, gdf Protein, gdf-5 Protein, GDF5 Protein, BDA1C Protein, BMP14 Protein, LAP4 Protein, OS5 Protein, SYM1B Protein, SYNS2 Protein, Cdmp-1 Protein, bp Protein, brp Protein, Cdmp1 Protein, growth differentiation factor 5 L homeolog Protein, growth differentiation factor 5 Protein, gdf5.L Protein, GDF5 Protein, Gdf5 Protein
- Background
- Growth differentiation factor 5(GDF-5) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This protein plays a role in chondrogenesis and chondrocyte metabolism, tendon and ligament tissue formation, and bone repair. It also increases the survival of neurones that respond to a neurotransmitter called dopamine, and is a potential therapeutic molecule associated with Parkinson's disease. GDF-5, fused to His-tag at N-terminus, was expressed as insoluble protein aggregate in E.coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer. Synonyms: Growth differentiation factor 5, BMP14, CDMP1, LAP4, OS5, SYNS2, Growth differentiation factor 5 Cartilage derived morphogenetic protein 1,. NCBI no.: NP_000548
- Molecular Weight
- 15.8 kDa (141aa), confirmed by MALDI-TOF.
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