CDK2AP1 Protein (AA 1-115) (His tag)
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- Target See all CDK2AP1 Proteins
- CDK2AP1 (Cyclin-Dependent Kinase 2 Associated Protein 1 (CDK2AP1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-115
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CDK2AP1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- CDK2AP1, 1-115aa, Human, His tag, E. coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product CDK2AP1 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 50% glycerol, 2mM DTT
- Storage
- 4 °C
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- Target
- CDK2AP1 (Cyclin-Dependent Kinase 2 Associated Protein 1 (CDK2AP1))
- Alternative Name
- CDK2AP1 (CDK2AP1 Products)
- Synonyms
- MGC64532 Protein, doc1 Protein, st19 Protein, doc-1 Protein, dorc1 Protein, p12doc-1 Protein, Apc10 Protein, Cdkap1 Protein, DORC1 Protein, Doc1 Protein, ST19 Protein, p12 Protein, DOC1 Protein, p12DOC-1 Protein, cyclin-dependent kinase 2 associated protein 1 S homeolog Protein, cyclin dependent kinase 2 associated protein 1 Protein, cyclin dependent kinase 2 associated protein 1 pseudogene Protein, cyclin-dependent kinase 2 associated protein 1 Protein, CDK2 (cyclin-dependent kinase 2)-associated protein 1 Protein, cdk2ap1.S Protein, CDK2AP1 Protein, LOC475806 Protein, cdk2ap1 Protein, Cdk2ap1 Protein
- Background
- CDK2AP1 is a specific CDK2-associated protein, which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. Also, interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggested the regulatory role in DNA replication during S phase of the cell cycle. A similar gene in hamster was isolated from, and functions as a growth suppressor of normal keratinocytes. Recombinant CDK2AP1 protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: CDKAP1, DOC1, CDKA1, Cyclin-dependent kinase 2 associated protein 1 CDK2 A1, CDK2 associated protein 1, CDK2AP1, Cyclin dependent kinase 2 associated protein 1 Deleted in oral cancer 1, DOC 1, DOC 1 related protein, DOC 1R, DOC1R, Putative oral cancer suppressor. NCBI no.: NP_004633
- Molecular Weight
- 16.6kDa (152aa), confirmed by MALDI-TOF.
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