SOD2 Protein (AA 25-222) (His tag)

Catalog No. ABIN666966

Product Details

Target: SOD2 (Superoxide Dismutase 2, Mitochondrial (SOD2))

Protein Type: Recombinant

Protein Characteristics: AA 25-222

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This SOD2 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Characteristics: SOD2, 25-222aa, Human, His tag, E.coli

Purity: > 95 % by SDS - PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol

Storage: 4 °C

Target Details

Target: SOD2 (Superoxide Dismutase 2, Mitochondrial (SOD2))

Alternative Name: SOD2 (SOD2 Products)

Synonyms: LOC100101896 Protein, MNSOD Protein, GB14346 Protein, sod2 Protein, MGC88869 Protein, Sod2 Protein, CG8905 Protein, Dmel\\CG8905 Protein, Mito SOD Protein, Mn SOD Protein, Mn-SOD Protein, Mn-SOD2 Protein, MnSOD Protein, MnSODII Protein, Mn[2+]SOD Protein, SOD Protein, SOD-2 Protein, SOD2 Protein, Sod-2 Protein, dSOD2 Protein, mitSOD2 Protein, mnSOD Protein, IPOB Protein, MVCD6 Protein, cb463 Protein, wu:fj33b01 Protein, zgc:73051 Protein, MnSOD Protein, manganese superoxide dismutase Protein, superoxide dismutase 2, mitochondrial Protein, superoxide dismutase 2 Protein, Mn superoxide dismutase Protein, Superoxide dismutase 2 (Mn) Protein, superoxide dismutase 2 L homeolog Protein, BDBG_07234 Protein, LOC100101896 Protein, MNSOD Protein, Sod2 Protein, sod2 Protein, LbMnSOD4 Protein, SOD2 Protein, LOC100282741 Protein, SOD-2 Protein, sod2.L Protein

Background: SOD2 is a member of the iron/manganese superoxide dismutase family. It is a mitochondrial matrix protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this protein have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Recombinant human SOD2 protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: IPOB, MNSOD, MVCD6, Superoxide dismutase [Mn], mitochondrial IPO B, Manganese SOD, Manganese superoxide dismutase, Mn SOD, SOD 2, SOD2, Superoxide dismutase [Mn] mitochondrial, Superoxide dismutase 2 mitochondrial, Superoxide Dismutase-2. NCBI no.: NP_001019636

Molecular Weight: 24.4kDa (219aa), confirmed by MALDI-TOF.

Pathways: Sensory Perception of Sound, Transition Metal Ion Homeostasis, Negative Regulation of intrinsic apoptotic Signaling