LAT2 Protein (AA 27-243) (His tag)
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- Target See all LAT2 Proteins
- LAT2 (Linker For Activation of T Cells Family, Member 2 (LAT2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 27-243
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This LAT2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- NTAL, 27-243aa, Human, His tag, E.coli
- Purity
- > 80 % by SDS - PAGE
- Top Product
- Discover our top product LAT2 Protein
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Linker For Activation of T Cells Family, Member 2 (LAT2) (AA 27-243) protein (His tag)
LAT2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Linker For Activation of T Cells Family, Member 2 (LAT2) (AA 1-243) protein (GST tag)LAT2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Linker For Activation of T Cells Family, Member 2 (LAT2) (AA 144-242) protein (GST tag)LAT2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 10% Glycerol
- Storage
- 4 °C
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- Target
- LAT2 (Linker For Activation of T Cells Family, Member 2 (LAT2))
- Alternative Name
- NTAL (LAT2 Products)
- Synonyms
- LAB Protein, NTAL Protein, WBSCR15 Protein, WBSCR5 Protein, WSCR5 Protein, LAT2 Protein, MGC139435 Protein, Ntal Protein, Wbscr5 Protein, AW125574 Protein, Wbscr15 Protein, linker for activation of T-cells family member 2 Protein, linker for activation of T cells family, member 2 Protein, LAT2 Protein, Lat2 Protein
- Background
- NTAL (non-T cell activation linker), as known as LAT2, is transmembrane adaptor protein (TRAP) associated with glycolipid-enriched membrane fractions (GEM or lipid rafts). This protein is primarily expressed in spleen and hematopoietic cells, such as B cells, mast cells, NK cells, and monocytes, but not resting T cells. Defects in NTAL may be a cause of certain cardiovascular and musculo-skeletal abnormalities observed in Williams-Beuren syndrome (WBS). Recombinant human NTAL, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: LAT2, HSPC046, LAB, WBSCR15, WBSCR5, WSCR5, Non-T-cell activation linker LAB, Lat2, Linker for activation of B cells, Linker for activation of T cells family member 2, Membrane associated adapter molecule, Non T cell activation linker, WBSCR 5, Wbscr15, Williams Beuren syndrome chromosome region 15, Williams Beuren syndrome chromosome region 5. NCBI no.: NP_115853
- Molecular Weight
- 26.2 kDa (238aa), confirmed by MALDI-TOF
- Pathways
- Fc-epsilon Receptor Signaling Pathway, BCR Signaling
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