LAT2 Protein (His tag)
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- Target See all LAT2 Proteins
- LAT2 (Linker For Activation of T Cells Family, Member 2 (LAT2))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This LAT2 protein is labelled with His tag.
- Purpose
- Recombinant Human LAT2 Protein (His Tag)
- Sequence
- Arg27-Ala243
- Characteristics
- Recombinant Human Linker for Activation of T-Cells Family Member 2 is produced by our Mammalian expression system and the target gene encoding Arg27-Ala243 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product LAT2 Protein
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Linker For Activation of T Cells Family, Member 2 (LAT2) (AA 27-243) protein (His tag)
LAT2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Linker For Activation of T Cells Family, Member 2 (LAT2) (AA 1-243) protein (GST tag)LAT2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Linker For Activation of T Cells Family, Member 2 (LAT2) (AA 144-242) protein (GST tag)LAT2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- LAT2 (Linker For Activation of T Cells Family, Member 2 (LAT2))
- Alternative Name
- LAT2 (LAT2 Products)
- Synonyms
- LAB Protein, NTAL Protein, WBSCR15 Protein, WBSCR5 Protein, WSCR5 Protein, LAT2 Protein, MGC139435 Protein, Ntal Protein, Wbscr5 Protein, AW125574 Protein, Wbscr15 Protein, linker for activation of T-cells family member 2 Protein, linker for activation of T cells family, member 2 Protein, LAT2 Protein, Lat2 Protein
- Background
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Background: Linker for Activation of T-Cells Family Member 2 (LAT2) is a single-pass type III membrane protein. LAT2 is highly expressed in the spleen, peripheral blood lymphocytes, and germinal centers of lymph nodes. LAT2 is involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. It may also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Coupleing activate of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2.
Synonym: Linker for Activation of T-Cells Family Member 2, Linker for Activation of B-Cells, Membrane-Associated Adapter Molecule, Non-T-Cell Activation Linker, Williams-Beuren Syndrome Chromosomal Region 15 Protein, Williams-Beuren Syndrome Chromosomal Region 5 Protein, LAT2, LAB, NTAL, WBS15, WBSCR15, WBSCR5
- Molecular Weight
- 25.0 kDa
- UniProt
- Q9GZY6
- Pathways
- Fc-epsilon Receptor Signaling Pathway, BCR Signaling
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