HPRT1 Protein (AA 1-218) (His tag)
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- Target See all HPRT1 Proteins
- HPRT1 (Hypoxanthine phosphoribosyltransferase 1 (HPRT1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-218
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This HPRT1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- HPRT1, 1-218aa, Human, His tag, E.coli
- Purity
- > 95 % by SDS-PAGE
- Top Product
- Discover our top product HPRT1 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing, 20% glycerol
- Storage
- 4 °C
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- Target
- HPRT1 (Hypoxanthine phosphoribosyltransferase 1 (HPRT1))
- Alternative Name
- HPRT1 (HPRT1 Products)
- Synonyms
- HGPRT Protein, HPRT Protein, C81579 Protein, HPGRT Protein, Hprt1 Protein, Hgprtase Protein, Hprt Protein, id:ibd1344 Protein, id:ibd5108 Protein, wu:fc10g09 Protein, zgc:56221 Protein, zgc:86608 Protein, hgprt Protein, hprt Protein, prtfdc1 Protein, hprt1 Protein, hprt1l Protein, zgc:55561 Protein, zgc:86771 Protein, hypoxanthine phosphoribosyltransferase 1 Protein, hypoxanthine guanine phosphoribosyl transferase Protein, hypoxanthine phosphoribosyltransferase 1 L homeolog Protein, phosphoribosyl transferase domain containing 1 Protein, HPRT1 Protein, Hprt Protein, Hprt1 Protein, hprt1 Protein, hprt1.L Protein, prtfdc1 Protein
- Background
- Hypoxanthine-guanine phosphoribosyltransferase, also known as HPRT1 has a central role in the generation of purine nucleotides through the purine salvage pathway. The enzyme primarily functions to salvage purines from degraded DNA to renewed purine synthesis. In this role, it acts as a catalyst in the reaction between guanine and phosphoribosyl pyrophosphate to form GMP. Recombinant human HPRT1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: HGPRT, HGPRTase, HPRT, Hypoxanthine-guanine phosphoribosyltransferase HPRT 1, HPRT1, Hypoxanthine guanine phosphoribosyltransferase, Hypoxanthine phosphoribosyltransferase 1 (Lesch Nyhan syndrome), Hypoxanthine phosphoribosyltransferase 1. NCBI no.: NP_000185
- Molecular Weight
- 26.7 kDa (238aa), confirmed by MALDI-TOF
- Pathways
- Ribonucleoside Biosynthetic Process
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