HNMT Protein (AA 1-292) (His tag)
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- Target See all HNMT Proteins
- HNMT (Histamine N-Methyltransferase (HNMT))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-292
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This HNMT protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- HNMT, 1-292 aa, Human, His-tagged, Recombinant, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product HNMT Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl(pH8.0) buffer containing 10% glycerol
- Storage
- 4 °C
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- Target
- HNMT (Histamine N-Methyltransferase (HNMT))
- Alternative Name
- HNMT (HNMT Products)
- Synonyms
- HMT Protein, HNMT-S1 Protein, HNMT-S2 Protein, hmt Protein, hnmt Protein, hnmt-s1 Protein, hnmt-s2 Protein, zgc:100917 Protein, HNMT Protein, 1500031F01Rik Protein, AI788969 Protein, HMT A Protein, hnmt-a Protein, hnmt-b Protein, histamine N-methyltransferase Protein, histamine N-methyltransferase S homeolog Protein, histamine N-methyltransferase-like Protein, histamine N-methyltransferase L homeolog Protein, HNMT Protein, hnmt.S Protein, hnmt Protein, Hnmt Protein, LOC100228106 Protein, hnmt.L Protein
- Background
- Histamine N-methyltransferase (HNMT) is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. HNMT inactivates histamine by N-methylation. Histamine is involved in regulation and modulation of immune response through the stimulation of four distinct subtypes of receptors, H1, H2, H3, and H4, present on the target cells. Histamine is inactivated by the histamine-metabolizing enzyme histamine N-methyltransferase (HNMT) in bronchus, kidney, and the central nervous system. It plays an important role in degrading histamine and in regulating the airway response to histamine. Recombinant human HNMT protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Histamine N-methyltransferase isoform 1 , HMT, HNMT-S1, HNMT-S2, Histamine N-methyltransferase isoform 1 EC 2.1.1.8, Histamine N methyltransferase, Hnmt, HNMT S1, HNMT S2. NCBI no.: NP_008826
- Molecular Weight
- 37 kDa (328 aa), confirmed by MALDI-TOF.
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