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TPI1 Protein (AA 1-249) (His tag)

TPI1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Catalog No. ABIN667249
  • Target See all TPI1 Proteins
    TPI1 (Triosephosphate Isomerase 1 (TPI1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-249
    Origin
    • 8
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 132
    • 7
    • 3
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This TPI1 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    TPI1, 1-249aa, Human, His tag, E.coli
    Purity
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product TPI1 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5mg/ml (determined by Bradford assay)
    Buffer
    Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 1mM DTT
    Storage
    4 °C
  • Target
    TPI1 (Triosephosphate Isomerase 1 (TPI1))
    Alternative Name
    TPI1 (TPI1 Products)
    Synonyms
    TIM Protein, TPI Protein, TIM1 Protein, hTIM Protein, tpi Protein, tpi1 Protein, TPI1 Protein, AI255506 Protein, Tpi Protein, Tpi-1 Protein, GB17473 Protein, Tim Protein, CG2171 Protein, Dmel\\CG2171 Protein, ND14 Protein, TPIS Protein, sgk Protein, wstd Protein, DrTPI-A Protein, DrTPI-B Protein, TIM-B Protein, cb179 Protein, wu:fb51c02 Protein, triosephosphate isomerase 1 Protein, timeless circadian regulator Protein, triosephosphate isomerase 1 S homeolog Protein, triosephosphate isomerase Protein, triose-phosphate isomerase Protein, Triose-phosphate isomerase Protein, triose-phosphate isomerase, putative Protein, timeless circadian clock Protein, Triose phosphate isomerase Protein, Triosephosphate isomerase Protein, triosephosphate isomerase 1a Protein, triosephosphate isomerase 1b Protein, TPI1 Protein, TIMELESS Protein, tpi1 Protein, Tpi1 Protein, tpi1.S Protein, Tpi Protein, tpiA Protein, CNE05000 Protein, Fnod_0738 Protein, Tlet_0996 Protein, SARE_RS16215 Protein, PKH_126640 Protein, Timeless Protein, tpi-1 Protein, tpi1a Protein, tpi1b Protein
    Background
    TPI1 (Triosephosphate isomerase) belongs to the triosephosphate isomerase family. TPI1 catalyzes the isomerization of glyceraldehydes 3-phosphate (G3P) and dihydroxy-acetone phosphate (DHAP) in glycolysis and gluconeogenesis. Defects in TPI1 are the cause of triosephosphate isomerase deficiency (TPI deficiency). TPI deficiency is an autosomal recessive disorder. It is the most severe clinical disorder of glycolysis. It is associated with neonatal jaundice, chronic hemolytic anemia, progressive neuromuscular dysfunction, cardiomyopathy and increased susceptibility to infection. Recombinant human TPI1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: triosephosphate isomerase, TPI, MGC88108, TIM, TPI, Triose-phosphate isomerase 1. Triosephosphate isomerase 1. NCBI no.: NP_000356
    Molecular Weight
    28.8kDa (269aa) confirmed by MALDI-TOF
    Pathways
    Cell RedoxHomeostasis
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