TPI1 Protein (His tag)

Catalog No. ABIN7319115

Product Details

Target: TPI1 (Triosephosphate Isomerase 1 (TPI1))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This TPI1 protein is labelled with His tag.

Purpose: Recombinant Human TPI1/TIM Protein (His Tag)

Sequence: Met 1-Gln249

Characteristics: Recombinant Human Triosephosphate Isomerase is produced by our E.coli expression system and the target gene encoding Met1-Gln249 is expressed with a 6His tag at the N-terminus.

Purity: > 90 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 1 mM DTT, 10 % Glycerol, pH 8.0.

Storage: -20 °C

Storage Comment: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Target Details

Target: TPI1 (Triosephosphate Isomerase 1 (TPI1))

Alternative Name: TPI1/TIM (TPI1 Products)

Synonyms: TIM Protein, TPI Protein, TIM1 Protein, hTIM Protein, tpi Protein, tpi1 Protein, TPI1 Protein, AI255506 Protein, Tpi Protein, Tpi-1 Protein, GB17473 Protein, Tim Protein, CG2171 Protein, Dmel\\CG2171 Protein, ND14 Protein, TPIS Protein, sgk Protein, wstd Protein, DrTPI-A Protein, DrTPI-B Protein, TIM-B Protein, cb179 Protein, wu:fb51c02 Protein, triosephosphate isomerase 1 Protein, timeless circadian regulator Protein, triosephosphate isomerase 1 S homeolog Protein, triosephosphate isomerase Protein, triose-phosphate isomerase Protein, Triose-phosphate isomerase Protein, triose-phosphate isomerase, putative Protein, timeless circadian clock Protein, Triose phosphate isomerase Protein, Triosephosphate isomerase Protein, triosephosphate isomerase 1a Protein, triosephosphate isomerase 1b Protein, TPI1 Protein, TIMELESS Protein, tpi1 Protein, Tpi1 Protein, tpi1.S Protein, Tpi Protein, tpiA Protein, CNE05000 Protein, Fnod_0738 Protein, Tlet_0996 Protein, SARE_RS16215 Protein, PKH_126640 Protein, Timeless Protein, tpi-1 Protein, tpi1a Protein, tpi1b Protein

Background:

Background: Triose-phosphate isomerase, also named Triose-phosphate isomerase, TPI and TIM, is an enzyme that catalyzes the reversible interconversion of the triose phosphate isomers dihydroxyacetone phosphate and D-glyceraldehyde 3-phosphate. TPI has been found in nearly every organism searched for the enzyme, including animals such as mammals and insects as well as in fungi, plants, and bacteria. However, some bacteria that do not perform glycolysis, like ureaplasmas, lack TPI. TPI plays an important role in glycolysis and is essential for efficient energy production. TPI deficiency is an autosomal recessive disorder and the most severe clinical disorder of glycolysis. Triose phosphate isomerase deficiency is associated with neonatal jaundice, chronic hemolytic anemia, progressive neuromuscular dysfunction, cardiomyopathy and increased susceptibility to infection and characterized by chronic hemolytic anemia.

Synonym: Triosephosphate Isomerase, TIM, Triose-Phosphate Isomerase, TPI1, TPI

Molecular Weight: 28.8 kDa

UniProt: P60174

Pathways: Cell RedoxHomeostasis