DNAJC19 Protein (AA 19-116) (His tag)

Catalog No. ABIN667349

Product Details

Target: DNAJC19 (DnaJ (Hsp40) Homolog, Subfamily C, Member 19 (DNAJC19))

Protein Type: Recombinant

Protein Characteristics: AA 19-116

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This DNAJC19 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Characteristics: DNAJC19, 19-116aa, Human, His tag, E.coli

Purity: > 90 % by SDS - PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 2mM DTT, 0.1M NaCl

Storage: 4 °C

Target Details

Target: DNAJC19 (DnaJ (Hsp40) Homolog, Subfamily C, Member 19 (DNAJC19))

Alternative Name: DNAJC19 (DNAJC19 Products)

Synonyms: PAM18 Protein, TIM14 Protein, TIMM14 Protein, 1810055D05Rik Protein, AA959924 Protein, Tim14 Protein, zgc:73251 Protein, DNAJC19 Protein, DKFZp469M2132 Protein, Gm15118 Protein, RGD1560220 Protein, DnaJ heat shock protein family (Hsp40) member C19 Protein, DnaJ (Hsp40) homolog, subfamily C, member 19 Protein, DnaJ heat shock protein family (Hsp40) member C19 L homeolog Protein, Pam18p Protein, DnaJ heat shock protein family (Hsp40) member C19, pseudogene Protein, DNAJC19 Protein, Dnajc19 Protein, dnajc19 Protein, dnajc19.L Protein, PAM18 Protein, Dnajc19-ps Protein

Background: DNAJC19 is a single-pass membrane protein that contains a J domain and is localized to the inner membrane of the mitochondrion. Expressed ubiquitously, DNAJC19 functions as a component of the mitochondrial DNAJC19 complex, which is responsible for the ATP-dependent translocation of select proteins from the inner mitochondrial membrane to the mitochondrial matrix. Defects in DNAJC19 are the cause of 3-methylglutaconic aciduria type 5 (MGA5), also known as dilated cardiomyopathy with ataxia (DCMA). Recombinant human DNAJC19 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Mitochondrial import inner membrane translocase subunit TIM14, Pam18, TIM14, TIMM14. NCBI no.: NP_660304

Molecular Weight: 15.1 kDa (135aa), confirmed by MALDI-TOF

Pathways: SARS-CoV-2 Protein Interactome