ALKBH2 Protein (AA 1-261) (His tag)
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- Target See all ALKBH2 Proteins
- ALKBH2 (AlkB, Alkylation Repair Homolog 2 (ALKBH2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-261
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This ALKBH2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- ALKBH2, 1-261aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product ALKBH2 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 30% glycerol
- Storage
- 4 °C
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- Target
- ALKBH2 (AlkB, Alkylation Repair Homolog 2 (ALKBH2))
- Alternative Name
- ALKBH2 (ALKBH2 Products)
- Synonyms
- si:dkey-65b12.2 Protein, ABH2 Protein, 9530023G02 Protein, AU016977 Protein, Abh2 Protein, mABH2 Protein, RGD1306377 Protein, alkB homolog 2, alpha-ketoglutarate dependent dioxygenase Protein, alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase Protein, ALKBH2 Protein, alkbh2 Protein, Alkbh2 Protein
- Background
- Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2, also known ALKBH2, belongs to the ALKB family. Expressed in heart, colon, liver, testis, ovary, prostate and small intestine, ALKBH2 uses iron as a cofactor and functions as a dioxygenase that catalyzes the repair of alkylated DNA and RNA containing 1-methyladenine and 3-meth-ylcytosine. ALKBH2 is functionally activated by ascorbate and requires oxygen and alpha-ketoglutarate for enzymatic activity. Recombinant human ALKBH2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2, ABH2, Oxy DC1. NCBI no.: NP_001138847
- Molecular Weight
- 31.4kDa (281aa), confirmed by MALDI-TOF
- Pathways
- DNA Damage Repair
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