SNIP1 Protein (AA 258-396) (His tag)
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- Target See all SNIP1 Proteins
- SNIP1 (Smad Nuclear Interacting Protein 1 (SNIP1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 258-396
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This SNIP1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- SNIP1, 258-396aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product SNIP1 Protein
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Smad Nuclear Interacting Protein 1 (SNIP1) (AA 1-396) protein (GST tag)
SNIP1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Smad Nuclear Interacting Protein 1 (SNIP1) (AA 258-396) protein (His tag)SNIP1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Smad Nuclear Interacting Protein 1 (SNIP1) (AA 1-396) protein (Strep Tag)Crystallography grade SNIP1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Smad Nuclear Interacting Protein 1 (SNIP1) (AA 1-383) protein (Strep Tag)Crystallography grade SNIP1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 20% glycerol, 100mM NaCl
- Storage
- 4 °C
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- Target
- SNIP1 (Smad Nuclear Interacting Protein 1 (SNIP1))
- Alternative Name
- SNIP1 (SNIP1 Products)
- Synonyms
- MGC75890 Protein, snip1a Protein, SNIP1 Protein, PMRED Protein, 2410133M08Rik Protein, Smad nuclear interacting protein 1 Protein, Smad nuclear interacting protein 1 S homeolog Protein, smad nuclear interacting protein 1 Protein, MYST/Esa1 associated factor 6 Protein, snip1 Protein, snip1.S Protein, SNIP1 Protein, CC1G_02914 Protein, PTRG_06240 Protein, MEAF6 Protein, Snip1 Protein
- Background
- SNIP1 is smad nuclear interacting protein contains a forkhead-associated (FHA) domain and acts as a nuclear inhibitor of CBP/p300. This protein is an inhibitor of the TGF-beta signal transduction pathway and to be important in suppressing transcriptional activation dependent on the co-activators CBP and p300. Inhibition of NF-kappa B activity is a function of the N-terminal domain of SNIP1 and involves competition of SNIP1 and the NF-kappa B subunit, RelA/p65, for binding to p300, similar to the mechanism of inhibition of Smad signaling by SNIP1. Recombinant human SNIP1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Smad nuclear interacting protein 1, FLJ12553, Splicing factor arginine/serine rich 4. NCBI no.: NP_078976
- Molecular Weight
- 18.8kDa (160aa), confirmed by MALDI-TOF
- Pathways
- SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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