Dual Specificity Phosphatase 3 (DUSP3) (AA 1-185) protein (His tag)
-
- Target See all Dual Specificity Phosphatase 3 (DUSP3) Proteins
- Dual Specificity Phosphatase 3 (DUSP3)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-185
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- His tag
- Application
- SDS-PAGE (SDS)
- Characteristics
- DUSP3, 1-185 aa , Human, His tag, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product DUSP3 Protein
-
Dual Specificity Phosphatase 3 (DUSP3) (AA 1-205) protein (His tag)
DUSP3 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Dual Specificity Phosphatase 3 (DUSP3) (AA 1-144) protein (GST tag)DUSP3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Dual Specificity Phosphatase 3 (DUSP3) (AA 1-185) protein (GST tag)DUSP3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Dual Specificity Phosphatase 3 (DUSP3) (AA 76-185) protein (GST tag)DUSP3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
-
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford)
- Buffer
- Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 2mM DTT, 0.15M NaCl.
- Storage
- 4 °C
-
- Target
- Dual Specificity Phosphatase 3 (DUSP3)
- Alternative Name
- DUSP3 (DUSP3 Products)
- Synonyms
- dusp3 Protein, si:bz18k17.3 Protein, si:rp71-18k17.3 Protein, VHR Protein, RGD1560049 Protein, 2210015O03Rik Protein, 5031436O03Rik Protein, T-DSP11 Protein, dual specificity phosphatase 3 Protein, dual specificity phosphatase 3b Protein, dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) Protein, DUSP3 Protein, dusp3b Protein, Dusp3 Protein
- Target Type
- Viral Protein
- Background
- DUSP3 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein kinase superfamily, which are associated with cellular proliferation and differentiation. DUSP3 is expressed in both breast and ovarian tissues. DUSP3 Shows activity both for tyrosine-protein phosphate and serine-protein phosphate, but displays a strong preference toward phosphotyrosines. Specifically dephosphorylates and inactivates ERK1 and ERK2. Recombinant human DUSP3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Dual specificity protein phosphatase 3, VHR. NCBI no.: NP_004081
- Molecular Weight
- 22.6 kDa (205aa), confirmed by MALDI-TOF
- Pathways
- Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
-
