FKBP1B Protein (AA 1-108) (His tag)
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- Target See all FKBP1B Proteins
- FKBP1B (FK506 Binding Protein 1B, 12.6 KDa (FKBP1B))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-108
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This FKBP1B protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- FKBP1B, 1-108aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product FKBP1B Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 1mM DTT
- Storage
- 4 °C
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- Target
- FKBP1B (FK506 Binding Protein 1B, 12.6 KDa (FKBP1B))
- Alternative Name
- FKBP1B (FKBP1B Products)
- Synonyms
- FKBP12.6 Protein, MGC68829 Protein, FKBP1B Protein, DKFZp459K1429 Protein, 12.6kDa Protein, AW494148 Protein, calstabin2 Protein, FKBP1L Protein, OTK4 Protein, PKBP1L Protein, PPIase Protein, FK506 binding protein 1B Protein, FK506 binding protein 1B L homeolog Protein, FK506 binding protein 1b Protein, FKBP1B Protein, fkbp1b.L Protein, fkbp1b Protein, Fkbp1b Protein
- Background
- FKBP1B, also known as peptidyl-prolyl cis-trans isomerase FKBP1B, is a member of the immunophilin protein family which plays a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 (tacrolimus) and rapamycin (sirolimus). It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. Recombinant human FKBP1B protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Peptidyl-prolyl cis-trans isomerase FKBP1B, FKBP12.6, FKBP1L, OTK4, PKBP1L, PPIase. NCBI no.: NP_004107
- Molecular Weight
- 14.2 kDa (130aa), confirmed by MALDI-TOF
- Pathways
- Hormone Transport, Negative Regulation of Hormone Secretion, Negative Regulation of Transporter Activity
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