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FKBP1B Protein (AA 1-108) (His tag)

FKBP1B Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Catalog No. ABIN667593
  • Target See all FKBP1B Proteins
    FKBP1B (FK506 Binding Protein 1B, 12.6 KDa (FKBP1B))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-108
    Origin
    • 4
    • 3
    • 2
    • 1
    • 1
    Human
    Source
    • 6
    • 3
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This FKBP1B protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    FKBP1B, 1-108aa, Human, His tag, E.coli
    Purity
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product FKBP1B Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 1mM DTT
    Storage
    4 °C
  • Target
    FKBP1B (FK506 Binding Protein 1B, 12.6 KDa (FKBP1B))
    Alternative Name
    FKBP1B (FKBP1B Products)
    Synonyms
    FKBP12.6 Protein, MGC68829 Protein, FKBP1B Protein, DKFZp459K1429 Protein, 12.6kDa Protein, AW494148 Protein, calstabin2 Protein, FKBP1L Protein, OTK4 Protein, PKBP1L Protein, PPIase Protein, FK506 binding protein 1B Protein, FK506 binding protein 1B L homeolog Protein, FK506 binding protein 1b Protein, FKBP1B Protein, fkbp1b.L Protein, fkbp1b Protein, Fkbp1b Protein
    Background
    FKBP1B, also known as peptidyl-prolyl cis-trans isomerase FKBP1B, is a member of the immunophilin protein family which plays a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 (tacrolimus) and rapamycin (sirolimus). It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. Recombinant human FKBP1B protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Peptidyl-prolyl cis-trans isomerase FKBP1B, FKBP12.6, FKBP1L, OTK4, PKBP1L, PPIase. NCBI no.: NP_004107
    Molecular Weight
    14.2 kDa (130aa), confirmed by MALDI-TOF
    Pathways
    Hormone Transport, Negative Regulation of Hormone Secretion, Negative Regulation of Transporter Activity
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