FKBP1B Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- Target See all FKBP1B Proteins
- FKBP1B (FK506 Binding Protein 1B, 12.6 KDa (FKBP1B))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This FKBP1B protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human FKBP1B / FKBP9 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product FKBP1B Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- FKBP1B (FK506 Binding Protein 1B, 12.6 KDa (FKBP1B))
- Alternative Name
- Fkbp1b,fkbp9 (FKBP1B Products)
- Synonyms
- FKBP12.6 Protein, MGC68829 Protein, FKBP1B Protein, DKFZp459K1429 Protein, 12.6kDa Protein, AW494148 Protein, calstabin2 Protein, FKBP1L Protein, OTK4 Protein, PKBP1L Protein, PPIase Protein, FK506 binding protein 1B Protein, FK506 binding protein 1B L homeolog Protein, FK506 binding protein 1b Protein, FKBP1B Protein, fkbp1b.L Protein, fkbp1b Protein, Fkbp1b Protein
- Background
- The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are two alternatively spliced transcript variants of this gene encoding different isoforms.
- Molecular Weight
- 8.6 kDa
- NCBI Accession
- NP_473374
- Pathways
- Hormone Transport, Negative Regulation of Hormone Secretion, Negative Regulation of Transporter Activity
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