Cyclin D2 Protein (CCND2) (AA 1-289) (His tag)

Catalog No. ABIN667637

Product Details

Target: Cyclin D2 (CCND2)

Protein Type: Recombinant

Protein Characteristics: AA 1-289

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This Cyclin D2 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Characteristics: CCND2, 1-289 aa , Human, His tag, E.coli

Purity: > 85 % by SDS - PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford)

Buffer: Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 2mM DTT, 1M Urea.

Storage: 4 °C

Target Details

Target: Cyclin D2 (CCND2)

Alternative Name: CCND2 (CCND2 Products)

Synonyms: si:ch211-240j22.2 Protein, ccnd2 Protein, CCND2 Protein, kiak0002 Protein, zgc:162280 Protein, LOC100224096 Protein, KIAK0002 Protein, BF642806 Protein, C86853 Protein, Vin-1 Protein, Vin1 Protein, cD2 Protein, 2600016F06Rik Protein, AI256817 Protein, cyclin D2, b Protein, cyclin D2 S homeolog Protein, cyclin D2 Protein, G1/S-specific cyclin-D2 Protein, cyclin D2, a Protein, cyclin D2 L homeolog Protein, ccnd2b Protein, ccnd2.S Protein, CCND2 Protein, ccnd2 Protein, ccnd2a Protein, Ccnd2 Protein, ccnd2.L Protein

Background: CCND2 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. High level expression of this protein was observed in ovarian and testicular tumors. Recombinant human CCND2 protein, fused to His-tag at N-terminus, was expressed in E.coli. Synonyms: Cyclin D2, KIAK0002, MGC102758, G1/S-specific cyclin-D2. NCBI no.: NP_001750

Molecular Weight: 35.6 kDa (313aa)

Pathways: Cell Division Cycle, Mitotic G1-G1/S Phases