TCEB1 Protein (AA 1-112) (His tag)
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- Target See all TCEB1 Proteins
- TCEB1 (Transcription Elongation Factor B (SIII), Polypeptide 1 (15kDa, Elongin C) (TCEB1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-112
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This TCEB1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- TCEB1, 1-112 aa, Human, His tag E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product TCEB1 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford)
- Buffer
- Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 1mM DTT, 0.15M NaCl.
- Storage
- 4 °C
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- Target
- TCEB1 (Transcription Elongation Factor B (SIII), Polypeptide 1 (15kDa, Elongin C) (TCEB1))
- Alternative Name
- TCEB1 (TCEB1 Products)
- Synonyms
- 2610043E24Rik Protein, 2610301I15Rik Protein, AA407206 Protein, AI987979 Protein, AW049146 Protein, SIII Protein, eloC Protein, TCEB1 Protein, fb09f09 Protein, wu:fb09f09 Protein, zgc:111990 Protein, zgc:92635 Protein, elongin C Protein, elongin C L homeolog Protein, transcription elongation factor B (SIII), polypeptide 1b Protein, Eloc Protein, eloc.L Protein, ELOC Protein, tceb1b Protein
- Background
- TCEB1 (elongin C) is a subunit of elongin, which is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template encoded arresting sites. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau(VHL) tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Recombinant human TCEB1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Transcription elongation factor B polypeptide 1, SIII, Elongin-C. NCBI no.: NP_005639
- Molecular Weight
- 14.6 kDa (132aa), confirmed by MALDI-TOF
- Pathways
- SARS-CoV-2 Protein Interactome
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