Geminin Protein (His tag)
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- Target See all Geminin (GMNN) Proteins
- Geminin (GMNN) (Geminin, DNA Replication Inhibitor (GMNN))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Geminin protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- Geminin, Human, Recombinant, His- tagged, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product GMNN Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris (pH 8.0), 100mM NaCl, 10% Glycerol
- Storage
- 4 °C
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- Target
- Geminin (GMNN) (Geminin, DNA Replication Inhibitor (GMNN))
- Alternative Name
- Geminin (GMNN Products)
- Synonyms
- CG3183 Protein, Dm Geminin Protein, Dm geminin Protein, Dmel\\CG3183 Protein, Gem Protein, Geminin Protein, anon-WO0257455.1 Protein, gem Protein, l(2)k14019 Protein, v(2)k09107 Protein, sb:cb254 Protein, zgc:66217 Protein, GB16871 Protein, GMNN Protein, geminin Protein, dyak_GLEANR_833 Protein, DyakGE24654 Protein, GE24654 Protein, LOC100049517 Protein, AW546347 Protein, geminin, DNA replication inhibitor Protein, CG3183 gene product from transcript CG3183-RA Protein, geminin Protein, GE24654 gene product from transcript GE24654-RA Protein, GMNN Protein, geminin Protein, gmnn Protein, LOC410093 Protein, Dyak\geminin Protein, Gmnn Protein
- Background
- Geminin is a 25 kDa protein, which inhibits DNA replication and is degraded during the mitotic phase of the cell cycle. Geminin controls replication by binding to the licensing factor Cdt1, and is involved in neural differentiation. In addition, geminin directly interacts with Six3 and Hox homeodomain proteins during embryogenesis and inhibits their functions. Synonyms: GMNN, Geminin, Geminin, DNA replication inhibitor, Gem, Geminin DNA replication inhibitor, OTTHUMP00000039393, RP3 369A17.3. NCBI no.: NP_056979
- Molecular Weight
- 27.6kDa (245aa), confirmed by MALDI-TOF.
- Pathways
- EGFR Signaling Pathway, DNA Replication
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