PTRH2 Protein (AA 64-179) (His tag)

Catalog No. ABIN667850

Product Details

Target: PTRH2 (Peptidyl-tRNA Hydrolase 2 (PTRH2))

Protein Type: Recombinant

Protein Characteristics: AA 64-179

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This PTRH2 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Characteristics: PTRH2, 64-179aa, Human, His tag, E.coli

Purity: > 95 % by SDS- PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris buffer (pH 8.0) containing 10% glycerol, 1mM DTT

Storage: 4 °C

Target Details

Target: PTRH2 (Peptidyl-tRNA Hydrolase 2 (PTRH2))

Alternative Name: PTRH2 (PTRH2 Products)

Synonyms: BIT1 Protein, PTH2 Protein, A230072I16Rik Protein, Bit1 Protein, CGI-147 Protein, wu:fj09f02 Protein, zgc:109954 Protein, RGD1306819 Protein, peptidyl-tRNA hydrolase 2 Protein, ptrh2 Protein, CC1G_10259 Protein, ANI_1_1036184 Protein, AOR_1_2082154 Protein, PTRH2 Protein, Ptrh2 Protein

Background: PTRH2 (peptidyl-tRNA hydrolase 2), also known as BIT1, is a mitochondrial protein. During apoptosis, PTRH2 is released from the mitochondria to the cytoplasm. Once in the cytoplasm, PTRH2 regulates the function of two transcriptional regulators, TLE5 and TLE1, thereby promoting caspase-independent cell death. The natural substrate for PTRH2 may be petidyl-tRNAs which drop off the ribosome during protein synthesis. Recombinant human PTRH2 protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Peptidyl-tRNA hydrolase 2, BIT1, PTH2, CGI-147, Bcl-2 inhibitor of transcription 1. NCBI no.: NP_057161

Molecular Weight: 14.9 kDa (137aa), confirmed by MALDI-TOF