G3BP1 Protein (AA 1-466) (His tag)

Catalog No. ABIN667856

Product Details

Target: G3BP1 (GTPase Activating Protein (SH3 Domain) Binding Protein 1 (G3BP1))

Protein Type: Recombinant

Protein Characteristics: AA 1-466

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This G3BP1 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Characteristics: G3BP1, 1-466aa, Human, His tag, E.coli

Purity: > 85 % by SDS - PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 2mM DTT, 100mM NaCl

Storage: 4 °C

Target Details

Target: G3BP1 (GTPase Activating Protein (SH3 Domain) Binding Protein 1 (G3BP1))

Alternative Name: G3BP1 (G3BP1 Products)

Synonyms: G3BP Protein, HDH-VIII Protein, fj17h05 Protein, zgc:56034 Protein, wu:fj17h05 Protein, g3bp Protein, MGC53271 Protein, G3BP1 Protein, G3bp Protein, RGD1310666 Protein, AI849976 Protein, B430204O07 Protein, C87777 Protein, mKIAA4115 Protein, G3BP stress granule assembly factor 1 Protein, GTPase activating protein (SH3 domain) binding protein 1 Protein, GTPase activating protein (SH3 domain) binding protein 1 L homeolog Protein, Ras-GTPase-activating protein SH3-domain-binding protein Protein, G3BP1 Protein, g3bp1 Protein, g3bp1.L Protein, LOC100304885 Protein, G3bp1 Protein

Background: G3BP1 is one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. And it cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR. Recombinant human G3BP1 protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: ATP dependent DNA helicase VIII, G3BP, G3BP1, GAP binding protein, GAP SH3 domain binding protein 1, HDH VIII, MGC111040, Ras GTPase activating protein binding protein 1, Ras GTPase activating protein SH3 domain binding protein, RasGAP associated endoribonuclease G3BP. NCBI no.: NP_005745

Molecular Weight: 53.2kDa (474aa), confirmed by MALDI-TOF

Pathways: SARS-CoV-2 Protein Interactome