POLL Protein (AA 1-300) (His tag)
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- Target See all POLL Proteins
- POLL (Polymerase (DNA Directed), lambda (POLL))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-300
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This POLL protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- POLL, 1-300aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product POLL Protein
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Polymerase (DNA Directed), lambda (POLL) (AA 1-300) protein (His tag)
POLL Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Polymerase (DNA Directed), lambda (POLL) (AA 1-575) protein (GST tag)POLL Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Polymerase (DNA Directed), lambda (POLL) protein (Myc-DYKDDDDK Tag)POLL Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 30% glycerol, 0.1M NaCl
- Storage
- 4 °C
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- Target
- POLL (Polymerase (DNA Directed), lambda (POLL))
- Alternative Name
- POLL (POLL Products)
- Synonyms
- T10O24.13 Protein, T10O24_13 Protein, zgc:66320 Protein, zgc:77901 Protein, wu:fe49a04 Protein, beta-n Protein, pol-kappa Protein, BETAN Protein, POLKAPPA Protein, 1110003P06Rik Protein, AV007317 Protein, DNA polymerase lambda (POLL) Protein, DNA polymerase lambda Protein, polymerase (DNA directed), lambda Protein, polymerase (DNA) lambda Protein, Pol{lambda} Protein, PTRG_00468 Protein, poll Protein, POLL Protein, MCYG_03796 Protein, LOC9325878 Protein, MGYG_02138 Protein, Poll Protein
- Background
- DNA polymerase lambda, also known as POLL, is a DNA polymerase involved in base excision repair (BER). POLL is a low-fidelity polymerase which plays a role in both spontaneous and DNA damage-induced mutagenesis. In addition, POLL may play a role in the mutagenic bypass of T-T dimers. Pol lambda possesses terminal transferase and 5’-deoxyribose-5-phosphate lyase activity. These activities have been found to be coordinated by PCNA and replication protein A. Recombinant human POLL protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: DNA polymerase lambda, BETA-N, POL-KAPPA. NCBI no.: AAH03548
- Molecular Weight
- 36 kDa (320aa), confirmed by MALDI-TOF
- Pathways
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
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