AFT1 Protein (AA 1-271) (His tag)
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- Target See all AFT1 Proteins
- AFT1 (Activating Transcription Factor 1 (AFT1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-271
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This AFT1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- ATF1, 1-271aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product AFT1 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 5mM DTT, 50% glycerol, 0.2M NaCl, 2mM EDTA
- Storage
- 4 °C
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- Target
- AFT1 (Activating Transcription Factor 1 (AFT1))
- Alternative Name
- ATF1 (AFT1 Products)
- Synonyms
- ews-atf1 Protein, fus/atf-1 Protein, treb36 Protein, ATF1 Protein, EWS-ATF1 Protein, FUS/ATF-1 Protein, TREB36 Protein, Atf-1 Protein, wu:fc92c07 Protein, zgc:64099 Protein, activating transcription factor 1 Protein, activating transcription factor 1 L homeolog Protein, atf1 Protein, ATF1 Protein, MGC85066 Protein, atf1.L Protein, Atf1 Protein
- Background
- Activating transcription factor 1, also known as ATF1, is a cyclic-AMP dependent transcription factor. ATF1 is expressed in a wide variety of cell types and is capable of dimerizing with CREB. MSK1 and MSK2 protein kinases are required for the stress-induced phosphorylation of transcription factors CREB and ATF1 in primary embryonic fibroblasts. Epidermal growth factor induction of c-jun expression requires ATF1 and MEF2 sites in the c-jun promoter. Recombinant human ATF1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Activating transcription factor 1, EWS-ATF1, FUS/ATF-1, TREB36. NCBI no.: NP_005162
- Molecular Weight
- 31.8 kDa (295aa) confirmed by MALDI-TOF
- Pathways
- Neurotrophin Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades
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