UBE2I Protein
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- Target See all UBE2I Proteins
- UBE2I (Ubiquitin-Conjugating Enzyme E2I (UBE2I))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- SDS-PAGE (SDS)
- Sequence
- MSGIALSRLA QERKAWRKDH PFGFVAVPTK NPDGTMNLMN WECAIPGKKG TPWEGGLFKL RMLFKDDYPS SPPKCKFEPP LFHPNVYPSG TVCLSILEED KDWRPAITIK QILLGIQELL NEPNIQDPAQ AEAYTIYCQN RVEYEKRVRA QAKKFAPS
- Characteristics
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Purified recombinant Human Ubc9 protein
Expression System: E.coli
Molecular weight on SDS-PAGE will appear higher. - Purity
- > 95 % pure
- Endotoxin Level
- < 1.0 EU per µg of protein (determined by LAL method)
- Top Product
- Discover our top product UBE2I Protein
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- Application Notes
- Ubiquitin protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Supplied as a liquid in 50 mM HEPES, pH7.5, containing 150 mM NaCl, 0 mM DTT, and 10 % glycerol.
- Preservative
- Dithiothreitol (DTT)
- Precaution of Use
- This product contains Dithiothreitol: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- RT/-20 °C
- Storage Comment
- Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
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- Target
- UBE2I (Ubiquitin-Conjugating Enzyme E2I (UBE2I))
- Alternative Name
- Ubc9 (UBE2I Products)
- Synonyms
- C358B7.1 Protein, P18 Protein, UBC9 Protein, ubc9 Protein, ube2ia Protein, zUbc9 Protein, 5830467E05Rik Protein, F830028O17Rik Protein, Ubce2i Protein, Ubce9 Protein, UbcE2A Protein, ubce9 Protein, T13J8.70 Protein, T13J8_70 Protein, UBIQUITIN-PROTEIN LIGASE Protein, ubiquitin conjugating enzyme 9 Protein, ubiquitin conjugating enzyme E2 I Protein, ubiquitin-conjugating enzyme E2Ib Protein, ubiquitin-conjugating enzyme E2L Protein, ubiquitin-conjugating enzyme E2I Protein, ubiquitin conjugating enzyme E2I S homeolog Protein, ubiquitin conjugating enzyme 9 Protein, SUMO-conjugating enzyme UBC9 Protein, UBE2I Protein, ube2ib Protein, UBE2L Protein, Ube2i Protein, ube2i.S Protein, UBC9 Protein, ubc-9 Protein, LOC108703134 Protein
- Background
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Human Ubc9 is homologous to ubiquitin-conjugating enzymes (E2s). However, instead of conjugating ubiquitin, it conjugates a ubiquitin homologue, small ubiquitin-like modifier 1(SUMO-1). And hUbc9 retains striking structural and functional conservation with yeast Ubc9. The ubiquitin-dependent protein degradation system has been recognized as a complete enzymatic pathway that is responsible for the selective degradation of abnormal and short-lived proteins. The conjugation of ubiquitin reuires the activities of ubiquitin-activating (E1) and -conjugating (E2) enzymes.
Alternative Names: EC 6.3.2 protein, UBE 2I protein, Ubiquitin conjugating enzyme UbcE2A protein, SUMO-conjugating enzyme UBC9 protein, Ubiquitin like protein SUMO 1 conjugating enzyme protein, Ubiquitin protein ligase E2I protein, Ubiquitin carrier protein 9 protein, UBCE 9 protein, SUMO1 protein ligase protein, Ubiquitin like protein SUMO1 conjugating enzyme protein, SUMO protein ligase protein, Ubiquitin protein ligase I protein, Human ubiquitin conjugating enzyme 9 protein, UBC9 homolog protein, p18 protein, SUMO 1 conjugating enzyme protein, , Ubiquitin conjugating enzyme E2I protein, UBCE9 protein, SUMO 1 protein ligase protein, Ubiquitin-conjugating enzyme E2I C358B7.1 protein, Ubiquitin-protein ligase I protein, UBC 9 protein, Ubiquitin carrier protein I protein, Ubiquitin carrier protein protein, SUMO1 conjugating enzyme protein, Ubiquitin conjugating enzyme 9 protein, p18 protein, Homologous to yeast UBC9 protein, UBE2I protein, Ubc9 protein, UBC9 protein, SUMO-protein ligase protein, SUMO conjugating enzyme UBC9 protein, Ubiquitin-conjugating enzyme E2 I protein - Molecular Weight
- 18 kDa (158 AA)
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Ubiquitin Proteasome Pathway
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