WISP3 Protein
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- Target See all WISP3 Proteins
- WISP3 (Wnt1 Inducible Signaling Pathway Protein 3 (WISP3))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Origin
- Human
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Source
- Escherichia coli (E. coli)
- Sequence
- TGPLDTTPEG RPGEVSDAPQ RKQFCHWPCK CPQQKPRCPP GVSLVRDGCG CCKICAKQPG EICNEADLCD PHKGLYCDYS VDRPRYETGV CAYLVAVGCE FNQVHYHNGQ VFQPNPLFSC LCVSGAIGCT PLFIPKLAGS HCSGAKGGKK SDQSNCSLEP LLQQLSTSYK TMPAYRNLPL IWKKKCLVQA TKWTPCSRTC GMGISNRVTN ENSNCEMRKE KRLCYIQPCD SNILKTIKIP KGKTCQPTFQ LSKAEKFVFS GCSSTQSYKP TFCGICLDKR CCIPNKSKMI TIQFDCPNEG SFKWKMLWIT SCVCQRNCRE PGDIFSELKI L
- Characteristics
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Purified recombinant Human WISP3 protein
Expression System: E.coli
Bioactivity: The ED50 was determined by the dose-dependant proliferation of the MCF-7 cell line. The expected ED50 for this effect is 0.2-0.3 µg/mL. - Purity
- > 98 % pure
- Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
- Top Product
- Discover our top product WISP3 Protein
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Wnt1 Inducible Signaling Pathway Protein 3 (WISP3) (Active) protein
WISP3 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Wnt1 Inducible Signaling Pathway Protein 3 (WISP3) (AA 1-372) protein (GST tag)WISP3 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Wnt1 Inducible Signaling Pathway Protein 3 (WISP3) (AA 24-354) protein (His tag)Crystallography grade WISP3 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute in 10 M Acetic Acid o a concentration of 0.1 - 1.0 mg/mL.
- Buffer
- Supplied lyophilized from 10 mM CH3COOH.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- Target
- WISP3 (Wnt1 Inducible Signaling Pathway Protein 3 (WISP3))
- Alternative Name
- WISP3 (WISP3 Products)
- Synonyms
- CCN6 Protein, LIBC Protein, PPAC Protein, PPD Protein, ENSMUSG00000062074 Protein, Gm735 Protein, WISP-3 Protein, RGD1564120 Protein, WISP3 Protein, si:dkey-119m7.6 Protein, WNT1 inducible signaling pathway protein 3 Protein, WISP3 Protein, Wisp3 Protein, wisp3 Protein
- Background
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WISP-3 is a member of the CCN family of secreted cysteine rich regulatory proteins. It is predominantly expressed in the adult kidney, testis and fetal kidney and weaker expression in placenta, ovary, prostate, small intestine, and skeletally-derived cells. WISP-3 is required for normal postnatal skeletal growth and cartilage homeostasis. Human WISP-3 is a 36.8 kDa protein containing 331 amino acid residues. It is composed of four distinct structural domains (modules), the IGF binding protein (IGFBP) domain, the von Willebrand Factor C (VWFC) domain, the thrombospondin type-1 repeat (TSP type-1) domain, and a C-terminal cystine knot-like (CTCK) domain.
Alternative Names: CCN6 protein, WISP 3 protein, WISP-3, WISP-3 protein, WNT-1 inducible signaling pathway protein-3 protein, WISP-3 protein, WISP 3, WISP3 - Pathways
- WNT Signaling, Growth Factor Binding
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