MAPT antibody (pSer214)

Catalog No. ABIN546569

Product Details anti-MAPT Antibody

Target: MAPT (Microtubule-Associated Protein tau (MAPT))

Binding Specificity: pSer214

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAPT antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit polyclonal antibody raised against synthetic phosphopeptide of MAPT.

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Antibody Reactive Against Synthetic Peptide.

Immunogen: Synthetic phosphopeptide corresponding to residues surrounding S214 of human MAPT.

Application Details

Application Notes: Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS, 150 mM NaCl, pH 7.4 (50 % glycerol, 0.02 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-MAPT antibody (ABIN546569)

Puig, Rey, Ferrer: "Individual and regional variations of phospho-tau species in progressive supranuclear palsy." in: Acta neuropathologica, Vol. 110, Issue 3, pp. 261-8, (2005) (PubMed).

Smet, Wieruszeski, Buée, Landrieu, Lippens: "Regulation of Pin1 peptidyl-prolyl cis/trans isomerase activity by its WW binding module on a multi-phosphorylated peptide of Tau protein." in: FEBS letters, Vol. 579, Issue 19, pp. 4159-64, (2005) (PubMed).

Götz, Chen, van Dorpe, Nitsch: "Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils." in: Science (New York, N.Y.), Vol. 293, Issue 5534, pp. 1491-5, (2001) (PubMed).

Target Details for MAPT

Target: MAPT (Microtubule-Associated Protein tau (MAPT))

Alternative Name: MAPT / TAU (MAPT Products)

Synonyms: DDPAC antibody, FTDP-17 antibody, MAPTL antibody, MSTD antibody, MTBT1 antibody, MTBT2 antibody, PPND antibody, TAU antibody, AI413597 antibody, AW045860 antibody, Mtapt antibody, Tau antibody, RNPTAU antibody, pTau antibody, tau antibody, xtp antibody, MAPT antibody, PHF-tau antibody, slc6a6 antibody, taut antibody, wu:fc26e12 antibody, microtubule associated protein tau antibody, microtubule-associated protein tau antibody, microtubule associated protein tau S homeolog antibody, Microtubule-associated protein tau antibody, solute carrier family 6 (neurotransmitter transporter), member 6b antibody, MAPT antibody, Mapt antibody, mapt.S antibody, LOC5580230 antibody, CpipJ_CPIJ013260 antibody, tau antibody, slc6a6b antibody

Gene ID: 4137

Pathways: MAPK Signaling, Microtubule Dynamics, M Phase, Regulation of Cell Size