MAPT antibody (AA 1-100)
Quick Overview for MAPT antibody (AA 1-100) (ABIN3021442)
Target
See all MAPT AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-100
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Sequence
- MAEPRQEFEV MEDHAGTYGL GDRKDQGGYT MHQDQEGDTD AGLKESPLQT PTEDGSEEPG SETSDAKSTP TAEDVTAPLV DEGAPGKQAA AQPHTEIPEG
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Cross-Reactivity
- Human, Mouse, Rat
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Characteristics
- Polyclonal Antibodies
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Immunogen
- A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Tau (NP_001116538).
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000,IHC,1:100 - 1:200,IF,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid freeze / thaw cycles
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- MAPT (Microtubule-Associated Protein tau (MAPT))
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Alternative Name
- MAPT
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Background
- This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.,DDPAC,FTDP-17,MAPTL,MSTD,MTBT1,MTBT2,PPND,PPP1R103,TAU,MAPT,Tau,Signal Transduction,MAPK-P38 Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Cytoskeleton,Microtubules,Neuroscience,Cell Type Marker,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Stem Cells,Neural Stem Cell marker,Neuron marker,Axon marker,MAPT
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Molecular Weight
- 32-45 kDa/78- 80 kDa
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Gene ID
- 4137
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UniProt
- P10636
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Pathways
- MAPK Signaling, Microtubule Dynamics, M Phase, Regulation of Cell Size
Target
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