IL-10 antibody
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- Target See all IL-10 (IL10) Antibodies
- IL-10 (IL10) (Interleukin 10 (IL10))
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Reactivity
- Human, Mouse
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This IL-10 antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC), Functional Studies (Func)
- Specificity
- Recognises both natural and recombinant human IL-10
- Purification
- Ion exchange chromatography
- Sterility
- 0.22 μm filtered
- Immunogen
- Recombinant human IL-10,Myeloma X63/AG.8653 x Balb/c spleen cells
- Clone
- B-S10
- Isotype
- IgG1 kappa
- Biological Activity Comment
- Blocks IL-10 induced inhibition of IL-6 synthesis on LPS activated monocytes
- Top Product
- Discover our top product IL10 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free
- Preservative
- Without preservative
- Storage
- 4 °C
- Storage Comment
- Stable at +2-8°C for 12 months. For longer storage freeze aliquots.
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CD3+CD4low and CD3+CD8low are induced by HLA-G: novel human peripheral blood suppressor T-cell subsets involved in transplant acceptance." in: Blood, Vol. 110, Issue 12, pp. 3936-48, (2007) (PubMed).
: "Effect of neutralizing antibodies to IL-10 and C5 on the renal damage caused by a pathogenic human anti-dsDNA antibody." in: Rheumatology (Oxford, England), Vol. 43, Issue 4, pp. 442-7, (2004) (PubMed).
: "Functional defects of dendritic cells in patients with CD40 deficiency." in: Blood, Vol. 102, Issue 12, pp. 4099-106, (2004) (PubMed).
: "Prevention of experimental autoimmune encephalomyelitis in common marmosets using an anti-IL-12p40 monoclonal antibody." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 169, Issue 11, pp. 6554-63, (2002) (PubMed).
: "Different expression of CD41 on human lymphoid and myeloid progenitors from adults and neonates." in: Blood, Vol. 97, Issue 7, pp. 2023-30, (2001) (PubMed).
: "Bacterial peptidoglycan and immune reactivity in the central nervous system in multiple sclerosis." in: Brain : a journal of neurology, Vol. 124, Issue Pt 8, pp. 1544-54, (2001) (PubMed).
: "Differential In situ cytokine profiles of Langerhans-like cells and T cells in Langerhans cell histiocytosis: abundant expression of cytokines relevant to disease and treatment." in: Blood, Vol. 94, Issue 12, pp. 4195-201, (2000) (PubMed).
: "Human nerve growth factor protects common marmosets against autoimmune encephalomyelitis by switching the balance of T helper cell type 1 and 2 cytokines within the central nervous system." in: The Journal of experimental medicine, Vol. 191, Issue 10, pp. 1799-806, (2000) (PubMed).
: "Defective regulation of IFNgamma and IL-12 by endogenous IL-10 in progressive MS." in: Neurology, Vol. 55, Issue 2, pp. 192-8, (2000) (PubMed).
: "Preincubation of human resting T cell clones with interleukin 10 strongly enhances their ability to produce cytokines after stimulation." in: Cytokine, Vol. 10, Issue 11, pp. 831-40, (1999) (PubMed).
: "B7/CD28-dependent IL-5 production by human resting T cells is inhibited by IL-10." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 152, Issue 9, pp. 4368-74, (1994) (PubMed).
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CD3+CD4low and CD3+CD8low are induced by HLA-G: novel human peripheral blood suppressor T-cell subsets involved in transplant acceptance." in: Blood, Vol. 110, Issue 12, pp. 3936-48, (2007) (PubMed).
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- Target
- IL-10 (IL10) (Interleukin 10 (IL10))
- Alternative Name
- IL-10 (IL10 Products)
- Synonyms
- CSIF antibody, GVHDS antibody, IL-10 antibody, IL10A antibody, TGIF antibody, Il-10 antibody, IL10X antibody, interleukin 10 antibody, IL10 antibody, Il10 antibody
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints
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