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Human Polyclonal ANGPTL6 Primary Antibody for ELISA, WB - ABIN1582384
Wang, Feng, Hu, Xie, Wang: Differentiating vitreous proteomes in proliferative diabetic retinopathy using high-performance liquid chromatography coupled to tandem mass spectrometry. in Experimental eye research 2013
developmental expression of Angptl1 (show ANGPTL1 Antibodies), 2 and 6 in zebrafish
High APOBEC3A (show APOBEC3A Antibodies) expression is associated with acute myelogenous leukemia.
SNPs in APOBEC3 (show APOBEC3F Antibodies) alter expression of APOBEC3A (show APOBEC3A Antibodies)/APOBEC3B (show APOBEC3B Antibodies) to affect somatic APOBEC-signature mutations.
Steady-state kinetic analysis reveals that APOBEC3A (A3A) discriminates against all ox-mCs by 3700-fold, arguing that ox-mC deamination does not contribute substantially to demethylation. A3A is, by contrast, highly proficient at C/mC deamination.
a solution-state model of APOBEC3A (show APOBEC3A Antibodies) interaction with its single-stranded DNA substrate obtained with the 'method of small changes', is reported.
exposures to relevant environmental factors might induce APOBEC3A (show APOBEC3A Antibodies) or APOBEC3B (show APOBEC3B Antibodies) expression above genotoxic levels and initiate tumorigenesis in a tissue-specific manner in the right cellular environment where ssDNA is available
Hyperthermia may induce regression of genital warts via APOBEC3A (show APOBEC3A Antibodies) expression in patients diagnosed with genital warts.
APOBEC3A (show APOBEC3A Antibodies) proteins were up regulated in genital warts cell cultures taken from patients diagnosed with human papillomavirus infections.
We have demonstrated that the APOBEC3A (show APOBEC3A Antibodies) gene of primates displays sequence variation consistent with a role in host defense against a changing pathogen or set of pathogens. Our data suggest that though APOBEC3A (show APOBEC3A Antibodies) potently restricts LINE-1 retroelements, the rapid evolution in APOBEC3A (show APOBEC3A Antibodies) was likely not driven by LINE-1.
crystal structures of human APOBEC3A (show APOBEC3A Antibodies) and a chimera of human APOBEC3B (show APOBEC3B Antibodies) and APOBEC3A (show APOBEC3A Antibodies) bound to ssDNA at 3.1-A and 1.7-A resolution, respectively.
By RNA sequencing, we show that specific inhibition of complex II (succinate dehydrogenase (show SDHA Antibodies); SDH (show SARDH Antibodies)) by atpenin A5 in normoxic conditions mimics hypoxia and induces hypoxic transcripts as well as APOBEC3A (show APOBEC3A Antibodies)-mediated RNA editing in human monocytes.
The present results provided evidence that polymorphisms of ANGPTL6 gene were associated with growth and slaughter traits.
mitochondrial OXPHOS function governs the expression of ANGPTL6, which is an essential factor for FGF21 (show FGF21 Antibodies) production in adipose tissue and cultured adipocytes.
In addition to pronounced angiogenesis and epidermal hyperplasia, marked enlargement of dermal lymphatic vessels was observed in UV-B-exposed Angptl6/AGF transgenic mice.
we show that (>80%) of the AGF-deficient mice die at about embryonic day 13, while the surviving AGF-deficient mice develop marked obesity, lipid accumulation in skeletal muscle and liver, and insulin (show INS Antibodies) resistance accompanied by reduced energy expenditure
Our results strongly suggest that AGF is an integrin ligand as well as a mitogenic growth factor and theoretically participates in cutaneous wound healing in a more complex mechanism.
Activation of an ERK1/2 (show MAPK1/3 Antibodies)-eNOS (show NOS3 Antibodies)-NO pathway is a crucial signaling mechanism by which angiopoietin-related growth factor increases blood flow through induction of angiogenesis and arteriogenesis.
This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. The protein encoded by this gene lacks the zinc binding activity of other family members. The protein plays a role in immunity, by restricting transmission of foreign DNA such as viruses. One mechanism of foreign DNA restriction is deamination of foreign double-stranded DNA cytidines to uridines, which leads to DNA degradation. However, other mechanisms are also thought to be involved, as anti-viral effect is not dependent on deaminase activity. Two transcript variants encoding different isoforms have been found for this gene.
, angiopoietin-related protein 6-like
, angiopoietin-like protein 6
, angiopoietin-related growth factor
, angiopoietin-related protein 5
, angiopoietin-related protein 6
, angiopoietin-like protein 6 alpha form
, angiopoietin-like protein 6 beta form
, Angiopoietin-related growth factor
, DNA dC->dU-editing enzyme APOBEC-3A
, phorbolin 1
, probable DNA dC->dU-editing enzyme APOBEC-3A
, actin-like protein 3
, actin-related protein 3
, actin-related protein 3 homolog (yest)