anti-Human Integrin beta 3 antibody for Immunoprecipitation

Recommended Integrin beta 3 Antibody (supplied by: Log in to see )

Antigen
Integrin beta 3 (ITGB3) Antibodies
  • CD61
  • GP3A
  • INGRB3
  • BDPLT16
  • BDPLT2
  • GPIIIa
  • GT
  • INTB3
  • integrin
  • GPIIIA
  • integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
  • integrin beta 3
  • integrin, beta 3
  • ITGB3
  • Itgb3
Reactivity
Human
584
240
203
28
27
25
24
19
16
13
6
5
4
4
4
3
2
2
2
2
2
2
1
1
1
1
Host
Mouse
368
231
52
29
19
2
1
Clonality
Monoclonal
Conjugate
This Integrin beta 3 antibody is un-conjugated
78
53
26
20
16
13
12
11
11
10
9
7
7
7
7
6
6
6
6
6
6
5
2
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
419
274
163
135
112
90
79
75
64
27
13
13
8
6
6
5
4
4
2
2
2
2
1
1
1
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Catalog No. ABIN1106489
$ 500.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN440347 BP ELISA FACS ICC IF IHC IHC (fro) IHC (p) IP Neut WB Mouse IgG1 Log in to see PM6-13 1
1 ABIN2472211 IHC (fro) FACS IP IHC (p) WB Mouse IgG1 Log in to see JM2E5 4
1 ABIN4327087 Func IA IHC IHC (fro) IHC (p) IP WB Mouse IgG1 Log in to see BV4 6
1 ABIN251125 ICC FACS IHC (fro) IF IP IHC Mouse IgG1 Log in to see MHF4 1
1 ABIN2704621 IC IF IP IHC WB Rabbit C-Term Log in to see Polyclonal
1 ABIN121347 FACS IHC (fro) IP Mouse IgG1 Log in to see F11 2
1 ABIN135712 FACS IP IHC WB Mouse IgG1 Log in to see PM6-13 1
1 ABIN1174439 ICC IHC IP WB Rabbit IgG AA 135-377 Log in to see Polyclonal
1 ABIN2472213 IHC (fro) FACS IP Mouse IgG1 Log in to see F11 3
1 ABIN1819775 FACS IHC (fro) IHC (p) IP WB FITC Mouse IgG1 Log in to see JM2E5
1 ABIN1834931 IHC (fro) FACS IHC (p) IP WB Mouse IgG1 Log in to see JM2E5
1 ABIN595991 FACS IP ELISA WB Mouse IgG1 Log in to see BV4
1 ABIN1102586 IHC (fro) FACS IHC (p) IP WB Mouse IgG1 Log in to see JM2E5
1 ABIN259991 FACS IHC (fro) IP IHC Mouse IgG1 Log in to see F11
1 ABIN601632 IHC (fro) FACS IHC (p) IP WB Mouse IgG1 Log in to see
1 ABIN198845 ICC FACS IP Mouse IgM Log in to see
1 ABIN210820 FACS IHC (fro) IP WB Mouse IgG1 Log in to see PM6-13
1 ABIN212732 FACS IHC (fro) IP Mouse IgG1 Log in to see
1 ABIN2624359 ICC IF IHC (p) IP WB Rabbit C-Term Log in to see Polyclonal
1 ABIN198306 FACS IHC (fro) IP WB Mouse IgG1 Log in to see PM6-13

Top referenced anti-Integrin beta 3 antibody for Immunoprecipitation

Similar anti-Integrin beta 3 Antibodies

Application / Reactivity Human
Biochemical Assay (BCA) 2 Antibodies
Blocking Peptide (BP) 1 Antibodies
Cytometry by Time of Flight (CyTOF) 6 Antibodies
ELISA 74 Antibodies
Enzyme Immunoassay (EIA) 5 Antibodies
Flow Cytometry (FACS) 307 Antibodies
Functional Studies (Func) 8 Antibodies
Immunoassay (IA) 1 Antibodies
Immunochromatography (IC) 5 Antibodies
Immunocytochemistry (ICC) 63 Antibodies
Immunofluorescence (IF) 91 Antibodies
Immunofluorescence (Cultured Cells) (IF (cc)) 13 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 5 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 27 Antibodies
Immunohistochemistry (IHC) 155 Antibodies
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 5 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 102 Antibodies

General

Antigen Integrin beta 3 (ITGB3) Antibodies
Reactivity Human
(584), (240), (203), (28), (27), (25), (24), (19), (16), (13), (6), (5), (4), (4), (4), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Host Mouse
(368), (231), (52), (29), (19), (2), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Integrin beta 3 antibody is un-conjugated
(78), (53), (26), (20), (16), (13), (12), (11), (11), (10), (9), (7), (7), (7), (7), (6), (6), (6), (6), (6), (6), (5), (2), (2), (2), (2), (2), (2), (2)
Application Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
(419), (274), (163), (135), (112), (90), (79), (75), (64), (27), (13), (13), (8), (6), (6), (5), (4), (4), (2), (2), (2), (2), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-Integrin beta 3 Antibody

Target Details Integrin beta 3 Application Details Handling ProductDetails: References for anti-Integrin beta 3 antibody (ABIN1106489) Images
Specificity The monoclonal antibody BV3 recognizes Human alpha-V/beta-3 integrin present on Human cells.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Also reacts to: Beta-3 Integrin
Purification Protein G
Clone BV3
Isotype IgG1

Target Details Integrin beta 3

Product Details anti-Integrin beta 3 Antibody Application Details Handling ProductDetails: References for anti-Integrin beta 3 antibody (ABIN1106489) Images back to top
Antigen
Alternative Name CD61 / ITGB3 (ITGB3 Antibody Abstract)
Background Integrins are a superfamily of αβ heterodimeric cell-surface adhesion receptors found in many species. They are expressed on a variety of cells and mediate numerous physiological processes, including inflammation, migration, adhesion and proliferation. The β3 family consist of 2 members: αIIbβ3 and αvβ3, which mediate cell-cell and cell-ECM interactions and are important for cellular migration, regulation of gene expression, cell survival, adhesion and differentiation. All processes which are involved in tissue development, angiogenesis and thrombosis. Each subunit consist of an extracellular domain, a single transmembrane segment and a cytoplasmic tail. They connect to the actin cytoskeleton via adaptor proteins that bind theircytoplasmic tails. Cell matrix adhesions also act as signaling units by their capacity to organize the actin cytoskeleton and to accumulate various signaling intermediates. Integrin αvβ3 was originally identified as the vitronectin receptor. Nevertheless, other ligands include fibrinogen, fibronectin, laminin, thrombospondin, Von Willebrand factor, tenascin, osteopontin and several forms of collagen. The interactions of integrin αvβ3 to those ligands is mediated by the RGD (Arg-Gly-Asp) sequence motif present in these proteins. Deregulation of β3 integrins is involved in e.g. autoimmune diseases, cardiovascular disorders, transplant rejection and tumorigenesis. In contribution to the latter, integrin αvβ3 contribute by supporting growth of small (tumor) blood vessels thereby potentiating the metastatic potential. Overexpression of integrin αvβ3 has been demonstrated in various tumors and activated endothelium.Synonyms: GP3A, GPIIIa, Integrin beta-3, Platelet membrane glycoprotein IIIa
Gene ID 3690
NCBI Accession NP_000203
UniProt P05106
Research Area CD Antigens, Surface Receptors of Immune Cells
Pathways Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex

Application Details

Product Details anti-Integrin beta 3 Antibody Target Details Integrin beta 3 Handling ProductDetails: References for anti-Integrin beta 3 antibody (ABIN1106489) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-Integrin beta 3 Antibody Target Details Integrin beta 3 Application Details ProductDetails: References for anti-Integrin beta 3 antibody (ABIN1106489) Images back to top
Concentration 0.1 mg/mL
Buffer PBS, 0.02 % Sodium Azide, 0.1 % BSA
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 2 - 8 °C.

ProductDetails: References for anti-Integrin beta 3 antibody (ABIN1106489)

Product Details anti-Integrin beta 3 Antibody Target Details Integrin beta 3 Application Details Handling Images back to top
Background publications

Merkel, Germershaus, Wada, Tarcha, Merdan, Kissel: "Integrin alphaVbeta3 targeted gene delivery using RGD peptidomimetic conjugates with copolymers of PEGylated poly(ethylene imine)." in: Bioconjugate chemistry, Vol. 20, Issue 6, pp. 1270-80, 2009

Dare, Griffith, Poitras, Wang, Dervin, Giulivi, Hincke: "Fibrin sealants from fresh or fresh/frozen plasma as scaffolds for in vitro articular cartilage regeneration." in: Tissue engineering. Part A, Vol. 15, Issue 8, pp. 2285-97, 2009

Newton, Girgenti, Collier, Duman: "Electroconvulsive seizure increases adult hippocampal angiogenesis in rats." in: The European journal of neuroscience, Vol. 24, Issue 3, pp. 819-28, 2006

Images

Product Details anti-Integrin beta 3 Antibody Target Details Integrin beta 3 Application Details Handling ProductDetails: References for anti-Integrin beta 3 antibody (ABIN1106489) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-Integrin beta 3 antibody (ITGB3) (ABIN1106489) anti-Integrin beta 3 (ITGB3) antibody