Browse our Protein Phosphatase 1, Regulatory Subunit 9B, Spinophilin (PPP1R9B) ELISA Kits

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Protein Phosphatase 1, Regulatory Subunit 9B, Spinophilin ELISA Kits (PPP1R9B)
On www.antibodies-online.com are 9 Protein Phosphatase 1, Regulatory Subunit 9B, Spinophilin (PPP1R9B) ELISA Kits from 6 different suppliers available. Additionally we are shipping Protein Phosphatase 1, Regulatory Subunit 9B, Spinophilin Antibodies (49) and Protein Phosphatase 1, Regulatory Subunit 9B, Spinophilin Proteins (4) and many more products for this protein. A total of 63 Protein Phosphatase 1, Regulatory Subunit 9B, Spinophilin products are currently listed.
Synonyms:
Neb2, PPP1R6, PPP1R9, SPINO, SPL, Spn
list all ELISA KIts Gene Name GeneID UniProt
PPP1R9B 84686 O35274
PPP1R9B 84687 Q96SB3
PPP1R9B 217124 Q6R891

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Protein Phosphatase 1, Regulatory Subunit 9B, Spinophilin (PPP1R9B) ELISA Kits by Reactivity

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More ELISA Kits for Protein Phosphatase 1, Regulatory Subunit 9B, Spinophilin Interaction Partners

Human Protein Phosphatase 1, Regulatory Subunit 9B, Spinophilin (PPP1R9B) interaction partners

  1. Data identify Spn (show SPN ELISA Kits) as a critical adhesion and signaling protein that is essential for modulating glioblastoma cell invasion in the brain microenvironment. Spn (show SPN ELISA Kits) suppresses brain tumor cell invasion, in part, via control of Rac1 GTPase (show RACGAP1 ELISA Kits) activities and invadopodia disassembly. Its C-terminus binds directly to the beta 8 integrin cytoplasmic tail.

  2. results indicate that spinophilin plays an important role in regulating the activity of Group I mGluRs as well as their influence on synaptic activity.

  3. Low spinophilin expression enhances aggressive biological behavior of breast cancer.

  4. Colorectal carcinoma expression of spinophilin expression determines cellular growth, cancer stemness and 5-flourouracil resistance.

  5. spinophilin might play a previously unrecognized role in the pathogenesis of head and neck squamous cell carcinoma

  6. Spn (show SPN ELISA Kits) downregulation contributes to a more aggressive biologic behavior, induces chemoresistance, and is associated with a poorer survival in patients with advanced stages of colorectal carcinoma.

  7. study found a substantial number of hepatocellular carcinomas (HCC (show FAM126A ELISA Kits)) show reduced or absent Spn (show SPN ELISA Kits) expression; the low expression of Spn (show SPN ELISA Kits) in tumour tissue is an independent negative prognostic factor for clinical outcome in HCC (show FAM126A ELISA Kits); spinophilin expression inversely correlates with proliferative activity

  8. Studies suggest that any change in substrate specificity of the spinophilin : PP1 (show PPA1 ELISA Kits) holoenzyme complex was probably due to direct modification of a PP1 (show PPA1 ELISA Kits) substrate binding surface.

  9. Spinophilin associates with both delta- and mu-OmicronR and G protein subunits in HEK293 cells participating in a multimeric signaling complex that displays a differential regulatory role in opioid receptor signaling.

  10. Spinophilin-deficient mice have enhanced antidepressant response to desipramine compared with wild-type controls.

Mouse (Murine) Protein Phosphatase 1, Regulatory Subunit 9B, Spinophilin (PPP1R9B) interaction partners

  1. two homologs neurabin and spinophilin play important yet distinct roles in the regulation of anxiety- and depression-like behaviors in an age-dependent manner.

  2. results indicate that spinophilin plays an important role in regulating the activity of Group I mGluRs as well as their influence on synaptic activity.

  3. COPS5 (show COPS5 ELISA Kits) overexpression reduced spinophilin in both the cortex (19%, p < 0.05) and the hippocampus (20%, p < 0.05), leading to significant deficits in learning and memory skills

  4. RanBP9 (show RANBP9 ELISA Kits) overexpression in transgenic mice led to striking reduction in the levels of spinophilin.

  5. Canonical betaAR-mediated signaling coupled to PKA activation results in phosphorylation of spinophilin, disrupting its interaction with alpha2AARs and accelerating alpha2AAR (show ADRA2A ELISA Kits) endocytic responses.

  6. Findings support the concept that the inhibitory effects of SPL (show SGPL1 ELISA Kits) on M3R (show CHRM3 ELISA Kits) activity are mediated by RGS4 (show RGS4 ELISA Kits).

  7. changes in spinophilin/CaMKII (show CAMK2G ELISA Kits) interactomes may contribute to changes in striatal dendritic spine density, morphology, and function during normal postnatal maturation and aging.

  8. these data suggest that spinophilin is an upstream regulator required for normal growth and excitation-contraction coupling, but is dispensable for beta-adrenergic stimulation of adult cardiomyocytes.

  9. Findings suggest that spinophilin restrains Angiotensin II-mediated sympathetic nervous system activation and is an unrecognized molecule with regard to central blood pressure control

  10. We suggest that Spn (show SPN ELISA Kits) may be the tumor suppressor gene located at 17q21.33 acting through Rb regulation.

Protein Phosphatase 1, Regulatory Subunit 9B, Spinophilin (PPP1R9B) Antigen Profile

Antigen Summary

Spinophilin is a regulatory subunit of protein phosphatase-1 catalytic subunit (PP1\; see MIM 176875) and is highly enriched in dendritic spines, specialized protrusions from dendritic shafts that receive most of the excitatory input in the central nervous system (Allen et al., 1997

Alternative names and synonyms associated with Protein Phosphatase 1, Regulatory Subunit 9B, Spinophilin (PPP1R9B)

  • protein phosphatase 1, regulatory subunit 9B (Ppp1r9b) Elisa Kit
  • protein phosphatase 1, regulatory subunit 9B (PPP1R9B) Elisa Kit
  • Neb2 Elisa Kit
  • PPP1R6 Elisa Kit
  • PPP1R9 Elisa Kit
  • SPINO Elisa Kit
  • SPL Elisa Kit
  • Spn Elisa Kit

Protein level used designations for PPP1R9B

PP1bp134 , neurabin 2 , neurabin-2 , neurabin-II , neural tissue-specific F-actin-binding protein II , nuerabin 2 , p130 , spinophilin , neurabin II , protein phosphatase 1, regulatory (inhibitor) subunit 9B , protein phosphatase 1, regulatory subunit 9B, spinophilin

GENE ID SPECIES
84686 Rattus norvegicus
84687 Homo sapiens
217124 Mus musculus
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