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Browse our BMP6 Proteins (BMP6)

Full name:
Bone Morphogenetic Protein 6 Proteins (BMP6)
On are 24 Bone Morphogenetic Protein 6 (BMP6) Proteins from 11 different suppliers available. Additionally we are shipping BMP6 Antibodies (113) and BMP6 Kits (56) and many more products for this protein. A total of 200 BMP6 products are currently listed.
BMP6, D13Wsu115e, VGR, vgr-1, Vgr1, zgc:113595
list all proteins Gene Name GeneID UniProt
BMP6 654 P22004
BMP6 25644 Q04906
BMP6 12161 P20722

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BMP6 Proteins (BMP6) by Origin

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Top referenced BMP6 Proteins

  1. Human BMP6 Protein expressed in HEK-293 - ABIN2666466 : Andriopoulos, Corradini, Xia, Faasse, Chen, Grgurevic, Knutson, Pietrangelo, Vukicevic, Lin, Babitt: BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism. in Nature genetics 2009 (PubMed)
    Show all 6 references for ABIN2666466

  2. Human BMP6 Protein expressed in Escherichia coli (E. coli) - ABIN413092 : Jukes, Both, Leusink, Sterk, van Blitterswijk, de Boer: Endochondral bone tissue engineering using embryonic stem cells. in Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)
    Show all 2 references for ABIN413092

More Proteins for BMP6 Interaction Partners

Human Bone Morphogenetic Protein 6 (BMP6) interaction partners

  1. Further investigation on clinical ESCC samples and non-tumorous adjacent tissue found that tumors with triple-positive BMP6, ALK2 (show ACRV1 Proteins) and BMPRII (show BMPR2 Proteins) had deeper growth than tumors with only BMP6 expression

  2. study shows that patients with CRA (show MTMR11 Proteins) had high expression of BMP6 and hepcidin (show HAMP Proteins) and low expression of s-HJV (show HFE2 Proteins). BMP6 was found to be negatively correlated with s-HJV (show HFE2 Proteins); both regulate hepcidin (show HAMP Proteins) expression and play important roles in the development of anemia.

  3. the combined delivery of VEGF (show VEGFA Proteins) and BMP-6 to the bone defect significantly enhanced bone repair through the enhancement of angiogenesis and the differentiation of endogenously recruited MSCs into the bone repair site.

  4. BMP-6 upregulates somatostatin receptor actions, leading to reduction of GnRH-induced secretion of luteinizing hormone.

  5. These observations suggest a novel role of BMP-6 in the inhibition of breast cancer metastasis by regulating secretion of MMPs(MMP-1 (show MMP1 Proteins)) in the tumor microenvironment.

  6. BMP-dependent physical interaction of VE-cadherin (show CDH5 Proteins) with the BMP receptor (show BMPR1A Proteins) ALK2 (show ACRV1 Proteins) (BMPRI) and BMPRII (show BMPR2 Proteins), resulting in stabilization of the BMP receptor (show BMPR1A Proteins) complex and, thereby, the support of BMP6-Smad (show SMAD1 Proteins) signaling.

  7. BMP6 and oxidized low-density lipoprotein independently and synergistically induced osteogenic differentiation and mineralization in vascular endothelial cells.

  8. Identify 3 heterozygous missense mutations in BMP6 in patients with unexplained iron overload. These mutations lead to loss of signaling to SMAD (show SMAD1 Proteins) proteins and reduced hepcidin (show HAMP Proteins) production.

  9. These results demonstrated that Hcy up-regulated hepcidin (show HAMP Proteins) expression through the BMP6/SMAD (show SMAD1 Proteins) pathway, suggesting a novel mechanism underlying the hyperhomocysteinemia-associated perturbation of iron homeostasis.

  10. demonstrate that BMP6 is associated with radiographic severity in AS, supporting the role wingless-type like/BMP pathway on radiographic progression in AS

Pig (Porcine) Bone Morphogenetic Protein 6 (BMP6) interaction partners

  1. Report temporal regulation of BMP6 mRNA expression in the oocyte, granulosa and theca cells of developing preovulatory follicles in the pig.

Mouse (Murine) Bone Morphogenetic Protein 6 (BMP6) interaction partners

  1. Western blot analysis demonstrated that following BMP2 (show BMP2 Proteins) and BMP7 (show BMP7 Proteins) cotransfection of MC3T3E1 cells, the protein expression levels of BMP2 (show BMP2 Proteins), BMP4 (show BMP4 Proteins), BMP6, BMP7 (show BMP7 Proteins), BMP9 (show GDF2 Proteins) and Wnt3a (show WNT3A Proteins) were increased compared with control cells

  2. In Bmp6-/- mice, iron activated endogenous compensatory mechanisms of other BMPs that were not sufficient for preventing hemochromatosis (show HFE Proteins) and bone loss.

  3. BMP6 expression levels may have potential as predictive markers for the progression of non-alcoholic liver disease.

  4. The expression of BMP6 in periodontal ligaments may contribute to interaction between the tooth and bone during the eruption and anchoring process.

  5. BMP-6 secreted by prostate cancer cells induces IL-6 (show IL6 Proteins) expression in macrophages; IL-6 (show IL6 Proteins), in turn, stimulates the neuroendocrine differentiation of prostate cancer cells.

  6. these data highlight a therapeutically innovative role for BMP6 by providing a means to enhance the amount of myogenic lineage derived brown fat.

  7. These results are consistent with novel mechanisms for regulating Bmp6 and Hamp1 (show HAMP Proteins) expression.

  8. Prostate cancer-derived BMP-6 stimulates tumor-associated macrophages to produce IL-1a (show IL1A Proteins) through a crosstalk between Smad1 (show SMAD1 Proteins) and NF-kB1 (show NFKB1 Proteins); IL-1a (show IL1A Proteins), in turn, promotes angiogenesis and prostate cancer growth.

  9. In addition to identifying BMP-6 expression in association with xerostomia and xerophthalmia in primary SS, results suggest that BMP-6-induced exocrine dysfunction in SS is independent of autoantibodies and immune activation associated with the disease.

  10. BMP-6 maintains epithelial polarity via intracellular signaling from basolaterally localized BMP receptors.

Cow (Bovine) Bone Morphogenetic Protein 6 (BMP6) interaction partners

  1. BMP6 and oxidized low-density lipoprotein independently and synergistically induced osteogenic differentiation and mineralization in vascular endothelial cells.

Goat Bone Morphogenetic Protein 6 (BMP6) interaction partners

  1. BMP-6 mRNA is increased during transition from primordial to primary/secondary follicles in the goat ovaries.

BMP6 Protein Profile

Protein Summary

The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity.

Alternative names and synonyms associated with BMP6

  • bone morphogenetic protein 6 (BMP6)
  • bone morphogenetic protein 6 (bmp6)
  • bone morphogenetic protein 6 (Bmp6)
  • bone morphogenetic protein 6 (LOC100354948)
  • BMP6 protein
  • D13Wsu115e protein
  • VGR protein
  • vgr-1 protein
  • Vgr1 protein
  • zgc:113595 protein

Protein level used designations for BMP6

bone morphogenetic protein 6 , BMP-6 , VG-1-R , VG-1-related protein , VGR-1 , Vg1-related sequence , vegetal related growth factor (TGFB-related) , vegetal-related (TGFB related) cytokine , bone morphogenic protein 6

100033934 Equus caballus
471851 Pan troglodytes
503761 Danio rerio
734440 Xenopus laevis
100127176 Xenopus (Silurana) tropicalis
100218097 Taeniopygia guttata
654 Homo sapiens
25644 Rattus norvegicus
100155536 Sus scrofa
12161 Mus musculus
478715 Canis lupus familiaris
617566 Bos taurus
100733783 Cavia porcellus
100860793 Capra hircus
420868 Gallus gallus
443174 Ovis aries
100354948 Oryctolagus cuniculus
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