Browse our anti-SH2D1B (SH2D1B) Antibodies

Full name:
anti-SH2 Domain Containing 1B Antibodies (SH2D1B)
On www.antibodies-online.com are 57 SH2 Domain Containing 1B (SH2D1B) Antibodies from 15 different suppliers available. Additionally we are shipping SH2D1B Proteins (5) and many more products for this protein. A total of 66 SH2D1B products are currently listed.
Synonyms:
EAT-2, EAT-2A, Eat2, Eat2a, RGD1563935, Sh2d1b, Sh2d1b1
list all antibodies Gene Name GeneID UniProt
SH2D1B 501869  
SH2D1B 117157 O14796
SH2D1B 26904  

Show all species

Show all synonyms

Most Popular Reactivities for anti-SH2D1B (SH2D1B) Antibodies

Select your species and application

anti-Rat (Rattus) SH2D1B Antibodies:

anti-Human SH2D1B Antibodies:

anti-Mouse (Murine) SH2D1B Antibodies:

All available anti-SH2D1B Antibodies

Go to our pre-filtered search.

Top referenced anti-SH2D1B Antibodies

  1. Human Polyclonal SH2D1B Primary Antibody for FACS, IHC (p) - ABIN653070 : Morra, Howie, Grande, Sayos, Wang, Wu, Engel, Terhorst: X-linked lymphoproliferative disease: a progressive immunodeficiency. in Annual review of immunology 2001 (PubMed)
    Show all 2 references for 653070

  2. Human Polyclonal SH2D1B Primary Antibody for EIA, FACS - ABIN954786 : Tangye, van de Weerdt, Avery, Hodgkin: CD84 is up-regulated on a major population of human memory B cells and recruits the SH2 domain containing proteins SAP and EAT-2. in European journal of immunology 2002 (PubMed)
    Show all 2 references for 954786

  3. Human Polyclonal SH2D1B Primary Antibody for ELISA, WB - ABIN335133 : Clarkson, Simmonds, Puklavec, Brown: Direct and indirect interactions of the cytoplasmic region of CD244 (2B4) in mice and humans with FYN kinase. in The Journal of biological chemistry 2007 (PubMed)

  4. Human Polyclonal SH2D1B Primary Antibody for ELISA, WB - ABIN408654 : Morra, Lu, Poy, Martin, Sayos, Calpe, Gullo, Howie, Rietdijk, Thompson, Coyle, Denny, Yaffe, Engel, Eck, Terhorst: Structural basis for the interaction of the free SH2 domain EAT-2 with SLAM receptors in hematopoietic cells. in The EMBO journal 2001 (PubMed)

More Antibodies against SH2D1B Interaction Partners

Human SH2 Domain Containing 1B (SH2D1B) interaction partners

  1. When compared with SAP (show APCS Antibodies), the other single SH2 domain protein in human, EAT2 shows similar binding energies to unphosphorylated ligands. This is inconsistent to the previous data showing low affinity of EAT2 toward unphosphorylated peptides compared to SAP (show APCS Antibodies) which shows high affinity

  2. Data indicate that Ewing's sarcoma-associated transcript-2 (EAT-2) over-expression increased the anti-tumor activity of NK cells against K562 tumor cell. targets.

  3. EAT-2 mediates its effects in natural killer cells by linking SLAM (show SLAMF1 Antibodies) family receptors to phospholipase Cgamma, calcium fluxes, and Erk (show EPHB2 Antibodies) kinase.

  4. NTB-A-mediated IFN-gamma production was greatly reduced in the absence of SLAM-associated protein (SAP), demonstrating that cytokine production and cytotoxicity are differentially dependent on SAP and possibly EAT-2

Mouse (Murine) SH2 Domain Containing 1B (SH2D1B) interaction partners

  1. EAT-2 negatively regulates cytokine production in dendritic cells downstream of SLAM (show SLAMF1 Antibodies) engagement and a genetic polymorphism that disturbs this process promotes the development of lupus.

  2. EAT-2 mediates its effects in natural killer cells by linking SLAM (show SLAMF1 Antibodies) family receptors to phospholipase Cgamma, calcium fluxes, and Erk (show EPHB2 Antibodies) kinase.

  3. EAT-2A and EAT-2B act as positive regulators of signaling lymphocyte activation molecule (show SLAMF1 Antibodies) family receptor-specific NK cell functions in C57BL/6 mice.

  4. Taken together, the data suggest that both EAT-2A and EAT-2B are adapters that recruit Src (show SRC Antibodies) kinases to SLAM (show SLAMF1 Antibodies) family receptors using a mechanism that is distinct from that of SAP (show APCS Antibodies).

  5. EAT-2 mediates CRACC (show SLAMF7 Antibodies) function. In the absence of EAT-2, CRACC (show SLAMF7 Antibodies) inhibited natural killer cell function.

SH2D1B Antigen Profile

Antigen Summary

By binding phosphotyrosines through its free SRC (MIM 190090) homology-2 (SH2) domain, EAT2 regulates signal transduction through receptors expressed on the surface of antigen-presenting cells (Morra et al., 2001

Alternative names and synonyms associated with SH2D1B

  • SH2 domain containing 1B (Sh2d1b) antibody
  • SH2 domain containing 1B (SH2D1B) antibody
  • SH2 domain protein 1B1 (Sh2d1b1) antibody
  • EAT-2 antibody
  • EAT-2A antibody
  • Eat2 antibody
  • Eat2a antibody
  • RGD1563935 antibody
  • Sh2d1b antibody
  • Sh2d1b1 antibody

Protein level used designations for SH2D1B

SH2 domain protein 1B1 , SH2 domain containing 1B , SH2 domain-containing protein 1B , EAT-2 , EWS/FLI1-activated transcript 2 , SH2 domain-containing molecule EAT2 , EWS/FLI1 activated transcript 2

GENE ID SPECIES
501869 Rattus norvegicus
418411 Gallus gallus
457464 Pan troglodytes
609474 Canis lupus familiaris
617485 Bos taurus
720097 Macaca mulatta
117157 Homo sapiens
26904 Mus musculus
Selected quality suppliers for anti-SH2D1B (SH2D1B) Antibodies
Did you look for something else?