SH2D1B antibody (AA 71-120)

Catalog No. ABIN1535361

This Rabbit Polyclonal antibody specifically detects SH2D1B in ELISA, IHC and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for SH2D1B antibody (AA 71-120) (ABIN1535361)

Target: SH2D1B (SH2 Domain Containing 1B (SH2D1B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SH2D1B antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-SH2D1B Antibody

Binding Specificity: AA 71-120

Purpose: EAT-2 Antibody

Specificity: EAT-2 Polyclonal Antibody detects endogenous levels of EAT-2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human SH2D1B. AA range:71-120

Isotype: IgG

Application Details

Application Notes: IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for SH2D1B

Target: SH2D1B (SH2 Domain Containing 1B (SH2D1B))

Alternative Name: SH2D1B

Background:

Synonyms: SH2D1B, EAT2, SH2 domain-containing protein 1B, EWS/FLI1-activated transcript 2, EAT-2

Background: By binding phosphotyrosines through its free SRC (MIM 190090) homology-2 (SH2) domain, EAT2 regulates signal transduction through receptors expressed on the surface of antigen-presenting cells (Morra et al., 2001 [PubMed 11689425]).[supplied by OMIM, Mar 2008],

Gene Name: SH2D1B

Protein Name: SH2 domain-containing protein 1B

Molecular Weight: 15 kDa

Gene ID: 117157

OMIM: 608510

UniProt: O14796

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process